RegulonDB RegulonDB 10.10: Operon Form
   

lgoR operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: lgoR
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: lgoR
Gene(s): lgoR   Genome Browser M3D Gene expression COLOMBOS
Note(s): In the presence of D-glucuronate, the binding affinity of ExuR is higher than that of UxuR to the lgoR/lgoD intergenic region. Under the same conditions, the binding of ExuR to the regulatory region is affected by the presence of UxuR Tutukina MN,2016
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: lgoRp4
+1: 4595947
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 96
Sequence: aacattcatcgtagacatgattcggctctccactttttgttgccttagatatcaatgaaaAtgaaaaatggcagcggaacg
                             -35                  -10       +1                   
Evidence: [ICWHO]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CRP-cyclic-AMP activator lgoRp4 4595902 4595915 40.0 aaaatcttttTTGTGAAAACACACgcataaaaat nd [GEA], [APIORCISFBSCS] [2]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote ExuR-α-D-galacturonate, α-D-glucuronate repressor lgoRp4 4595807 4595824 132.5 tttacgccacAATGTGATTAACCAGGTCattgatgata nd [BPP] [4]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote UxuR repressor lgoRp4 4595807 4595824 132.5 tttacgccacAATGTGATTAACCAGGTCattgatgata nd [GEA], [BPP] [3]





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