RegulonDB RegulonDB 11.2: Operon Form

ldtD operon and associated TUs in Escherichia coli K-12 genome

Name: ldtD
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: ldtD
Gene(s): ldtD   Genome Browser M3D Gene expression COLOMBOS
Note(s): Analysis of gene expression has proved that under NlpE lipoprotein overexpression, the presence of the protein CpxR causes increased transcription of the ycbB gene Raivio TL,2013
ldtD transcription is upregulated in the presence of epigallocatechin gallate (EGCG) through CpxR Nie T, Zhang C, Huang A, Li P,2018
A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for ldtD . This structure could regulate the expression of the gene, as observed for hemL gene expression Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X,2020.
Evidence: [COMP-AINF] Inferred computationally without human oversight
Name: ldtDp
+1: 980931
Distance from start of the gene: 116
Sequence: tctttaaacttctttacattaggttatgtaaaaacgtatcggcgtttatatactgaagatAagcctgatgagtaacaggct
Reference(s): [1] Mendoza-Vargas A., et al., 2009
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CpxR-phosphorylated activator ldtDp 980732 980747 -192.0 gatttgcgccGCAACTCCCTGAAACGcttccaggaa nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [2], [3]