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| Operon |  |
|---|---|
| Name: | btsT |
| This page displays every known transcription unit of this operon and their known regulation. | |
| Name: | btsT | |||||||||
| Synonym(s): | yjiY | |||||||||
| Gene(s): | btsT Genome Browser M3D Gene expression COLOMBOS | |||||||||
| Note(s): | The btsT gene belongs to the CstA superfamily of transporters, and it is strongly induced at the onset of the stationary growth phase, which requires cAMP and the cAMP receptor protein CRP Kraxenberger T,2012 btsT was expressed after growth on amino acids or peptides as carbon sources Kraxenberger T,2012 A functional link between the two systems provides positive feedback between YpdA/YhjX and btsT transcription, while yhjX is negatively regulated by BtsS/BtsT activity Behr S,2014. Behr S, Brameyer S, Witting M, Schmitt-Kopplin P, Jung K,2017 A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for btsT. This structure could regulate the expression of the gene, as observed for hemL gene expression Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X,2020. |
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| Evidence: | [ICWHO] Inferred computationally without human oversight | |||||||||
| Promoter | ||||||||||
| Name: | yjiYp | |||||||||
| +1: | 4591367 | |||||||||
| Sigma Factor: | Sigma38 Sigmulon | |||||||||
| Distance from start of the gene: | 88 | |||||||||
| Sequence: |
aaataaccactcagttatttaccttactttacgcgcgcgtaactctggcaacatcactacAggatagcggtcaatttacct -35 -10 +1 |
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| Evidence: |
[IHBCE] [TIM] |
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| Reference(s): | [1] Kraxenberger T., et al., 2012 | |||||||||
| Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
| proximal | BtsR-Phosphorylated | activator | yjiYp | 4591415 | 4591444 | -62.0 | ccgcaaaactGACCGCTTACATCCCTAAAATAACCACTCAgttatttacc | nd | [GEA], [AIBSPD], [BPP], [SM] | [1], [2] |
| Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
| remote | CRP-cyclic-AMP | activator | yjiYp | 4591489 | 4591511 | -132.5 | tcacaatataAATATGTGATATGAATCACATATttatcgtcac | nd | [GEA], [AIBSCS], [SM] | [1] |
| RNA cis-regulatory element | |
|---|
| Regulation, transcriptional elongation | |
| Attenuator type: | Translational |
| Strand: | reverse |
| Structure type | Energy | LeftPos | RightPos | Sequence (RNA-strand) | |
|---|---|---|---|---|---|
| terminator | -6.5 | 4591306 | 4591326 | aacgcaaaccTAGAACGGCTTCGGCCAACTattaatcaat |
| Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos" |
| Reference(s) |
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|---|---|
[IHBCE] Inferred by a human based on computational evidence