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Name: | acnA |
Gene(s): | ymiC, acnA Genome Browser M3D Gene expression COLOMBOS |
Note(s): | The expresion of the acnA gene is induced under oxidative stress, although this induction is not early after the stress is generated Lu C,2003. SoxS is a regulator that participates in controlling several genes involved in the response to oxidative stress. SoxS facilitates the binding of RNA polymerase to some promoters, including the acnA promoter, during low iron availability Fuentes AM,2001 |
Evidence: | [LTED] Length of transcript experimentally determined |
Reference(s): | [1] Cunningham L., et al., 1997 |
Promoter | |
Name: | acnAp1 |
+1: | 1335424 |
Sigma Factor: | Sigma38, Sigma70 |
Distance from start of the gene: | 148 |
Sequence: |
aatgttccgtcgttattccagacgactggcaactaacatcgcagcagcaagcctttatagAactgtttgctgaagatgatc -35 -10 +1 |
Evidence: |
[HIPP] [TIM] |
Reference(s): | [1] Cunningham L., et al., 1997 |
Name: | acnA |
Gene(s): | acnA Genome Browser M3D Gene expression COLOMBOS |
Note(s): | The expresion of the acnA gene is induced under oxidative stress, although this induction is not early after the stress is generated Lu C,2003. SoxS is a regulator that participates in controlling several genes involved in the response to oxidative stress. SoxS facilitates the binding of RNA polymerase to some promoters, including the acnA promoter, during low iron availability Fuentes AM,2001 |
Evidence: | [LTED] Length of transcript experimentally determined |
Reference(s): | [1] Cunningham L., et al., 1997 |
Promoter | |
Name: | acnAp2 |
+1: | 1335781 |
Sigma Factor: | Sigma70 Sigmulon |
Distance from start of the gene: | 50 |
Sequence: |
tcttttatcaatttgggttgttatcaaatcgttacgcgatgtttgtgttatctttaatatTcaccctgaagagaatcaggg -35 -10 +1 |
Evidence: |
[HIPP] [TIM] |
Reference(s): |
[1] Cunningham L., et al., 1997 [2] Mendoza-Vargas A., et al., 2009 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | ArcA-Phosphorylated | repressor | acnAp2 | 1335740 | 1335754 | -34.0 | aatttgggttGTTATCAAATCGTTAcgcgatgttt | nd | [APIORCISFBSCS], [CV(GEA/ROMA)], [GEA] | [1] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | CRP-cAMP | activator | acnAp2 | 1335730 | 1335751 | -40.5 | ctcttttatcAATTTGGGTTGTTATCAAATCGttacgcgatg | nd | [APIORCISFBSCS], [CV(GEA/ROMA)], [GEA] | [1] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | FNR | repressor | acnAp2 | 1335734 | 1335747 | -40.5 | tttatcaattTGGGTTGTTATCAAatcgttacgc | nd | [APIORCISFBSCS], [CV(GEA/ROMA)], [GEA] | [1] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | MarA | activator | acnAp2 | 1335720 | 1335740 | -51.5 | aaggtttctcCTCTTTTATCAATTTGGGTTGttatcaaatc | nd | [APIORCISFBSCS], [BPP], [CV(CHIP-SV/GEA/ROMA)], [CV(GEA/ROMA)], [GEA] | [3], [4] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | Rob | activator | acnAp2 | 1335720 | 1335740 | -51.5 | aaggtttctcCTCTTTTATCAATTTGGGTTGttatcaaatc | nd | [APIORCISFBSCS], [CV(GEA/ROMA)], [GEA] | [3] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | SoxS | activator | acnAp2 | 1335720 | 1335740 | -51.5 | aaggtttctcCTCTTTTATCAATTTGGGTTGttatcaaatc | nd | [APIORCISFBSCS], [BPP], , [CV(CHIP-SV/GEA/ROMA)], [CV(GEA/ROMA)], [GEA], [IHBCE], | [3], [4], [5] |
Note(s): | 1Even though the FruR site has not been determined for the acnA gene, the FruR effect in its transcription is correlated. It has been proposed that FruR affects the acnAp2 promoter because this is responsible for the basal level of acnA during exponential growth as well as redox stress Cunningham L,1997. 7Even though the FruR site has not been determined for the acnA gene, the FruR effect in its transcription is correlated. It has been proposed that FruR affects the acnAp2 promoter because this is responsible for the basal level of acnA during exponential growth as well as redox stress Cunningham L,1997. |
Name: | acnA |
Gene(s): | acnA Genome Browser M3D Gene expression COLOMBOS |
Note(s): | The transcription of the gene acnA is enhanced under high oxygen saturation (300%) in the absence of the superoxide dismutase proteins SodA and SodB Baez A,2013 |
Evidence: | [IC] Inferred by curator |
Promoter | |
Name: | acnAp3 |
+1: | 1335827 |
Distance from start of the gene: | 4 |
Sequence: |
gttatctttaatattcaccctgaagagaatcagggcttcgcaaccctgtcattaaggaggAgctatgtcgtcaaccctacg |
Evidence: | [HTIM] |
Reference(s): | [2] Mendoza-Vargas A., et al., 2009 |
Regulation by sRNA | ![]() |
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Small RNA name (Regulator) | Regulation type | Mechanism | Function | Binding Sites | Evidence | Reference | |||
---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Sequence (RNA-strand) | |||||||
ryhB | antisense | post-transcriptional regulation | repressor | [GEA] [HIFS] [IMP] |
[6] |
Notes: "The provided sequence is that of the RNA strand,i.e. 'U's are showed instead the 'T'" |
Reference(s) |
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