RegulonDB RegulonDB 10.10: Operon Form
   

rdcAB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: rdcAB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: rdcAB
Gene(s): rdcA, rdcB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: rdcAp2
+1: 4327064
Sigma Factor: Sigma28 Sigmulon
Distance from start of the gene: 71
Sequence: atttattctgataaaaaacaacacactaaatataaaattatttcttgcagtaattataaaAgccgaaaacagaactcaaaa
                           -35                 -10          +1                   
Note(s): The sequence of this promoter has been defined, by computational analyses, from the consensus sequence of the σ28 (σF) promoters: TAAAGTTT in the -35 box and GCCGATAA in the -10 box Yu HH,2006. Thus, we assigned a putative transcription start site for this promoter based on the observation that the majority of the σ28 promoters, determined experimentally, present an important -10 motif (5'-CGA-3') at the positions -12 to -10 and a distance of 6 nucleotides between the transcription start site and the -10 box Yu HH, Di Russo EG, Rounds MA, Tan M,2006. Yu HH,2006. Park K,2001.
Evidence: [HIPP]
[ICWHO]
[IHBCE]
Reference(s): [1] Huerta AM., et al., 2003
[2] Zhao K., et al., 2007


Transcription unit       
Name: rdcAB
Synonym(s): yjdA-yjcZ
Gene(s): rdcA, rdcB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: rdcAp1
+1: 4327079
Sigma Factor: Sigma28 Sigmulon
Distance from start of the gene: 56
Sequence: aaacaacacactaaatataaaattatttcttgcagtaattataaaagccgaaaacagaacTcaaaaacaatctggctaaat
                            -35                -10          +1                   
Note(s): The sequence of this promoter has been defined, by computational analyses, from the consensus sequence of the σ28 (σF) promoters: TAAAGTTT in the -35 box and GCCGATAA in the -10 box Yu HH,2006. Thus, we assigned a putative transcription start site for this promoter based on the observation that the majority of the σ28 promoters, determined experimentally, present an important -10 motif (5'-CGA-3') at the positions -12 to -10 and a distance of 6 nucleotides between the transcription start site and the -10 box Yu HH, Di Russo EG, Rounds MA, Tan M,2006. Yu HH,2006. Park K,2001.
Evidence: [HIPP]
[ICWHO]
[IHBCE]
Reference(s): [1] Huerta AM., et al., 2003
[2] Zhao K., et al., 2007


Evidence    

 [HIPP] Human inference of promoter position

 [ICWHO] Inferred computationally without human oversight

 [IHBCE] Inferred by a human based on computational evidence


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Zhao K., Liu M., Burgess RR., 2007, Adaptation in bacterial flagellar and motility systems: from regulon members to 'foraging'-like behavior in E. coli., Nucleic Acids Res 35(13):4441-52

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