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Synonyms: CpxR-phosphorylated, CpxR |
Summary:
The regulatory protein CpxR appears to control at least 100 operons [5]. Some of these operons are involved in cellular functions, such as "conjugative plasmid gene expression" (cpx) [24, 25], the envelope stress response system, pilus assembly, secretion, motility and chemotaxis, adherence, biofilm development, multidrug resistance and efflux [26], and the copper-responsive regulatory system [3], among others. In pathogenic bacteria it controls genes involved in invasion of host cells [27]. Sometimes, CpxR acts to modulate the action of the main activators or repressors of some promoters [26]. CpxR is the response regulator in the two-component regulatory system comprised of CpxR and CpxA [28]. Read more > |
Transcription factor | ![]() ![]() |
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TF conformation(s): |
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Evolutionary Family: | OmpR | ||||||||||||||||||
Sensing class: | External-Two-component systems | ||||||||||||||||||
Connectivity class: | Local Regulator | ||||||||||||||||||
Gene name: | cpxR | ||||||||||||||||||
Genome position: | 4104972-4105670 | ||||||||||||||||||
Length: | 699 bp / 232 aa | ||||||||||||||||||
Operon name: | cpxRA | ||||||||||||||||||
TU(s) encoding the TF: |
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Transcription factor regulation |
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Functional conformation | Function | Promoter | Sigma factor | Central Rel-Pos | Distance to first Gene | Genes | Sequence![]() |
LeftPos | RightPos | Evidence (Confirmed, Strong, Weak) | References | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CpxR-phosphorylated | activator | acrDp2 | Sigma54 | -127.5 | -172.5 | acrD |
ggagggtgagGAAAGTCAGTTAATGTAATgcctcctact
|
2587414 | 2587432 | [GEA], [IC], [BPP], [IC] | [4] | |
CpxR-phosphorylated | activator | acrDp2 | Sigma54 | -98.0 | -143.0 | acrD |
tcctactgacCAAAGAATACTTGCacttaaggtt
|
2587446 | 2587459 | [IC], [BPP], [IC] | [4] | |
CpxR-phosphorylated | activator | acrDp2 | Sigma54 | -66.0 | -111.0 | acrD |
ggttcagtatAAAAGGGCATGATAATTTacattaactc
|
2587476 | 2587493 | [GEA], [IC], [BPP], [IC] | [4] | |
CpxR-phosphorylated | activator | aroGp | Sigma70 | -38.0 | -80.0 | aroG |
cgttcatagtGTAAAACCCCGTTTAcacattctga
|
785546 | 785560 | [APIORCISFBSCS], [BPP] | [3] | |
CpxR-phosphorylated | activator | bacAp | Sigma24 | -292.0 | -336.0 | bacA |
tgggataaccGTAAAGCGGCGAAAAgtgatgatgt
|
3204460 | 3204474 | [ICA] | [5] | |
CpxR-phosphorylated | repressor | bamEp | Sigma24 | 11.0 | -109.0 | bamE |
agagtaaacaGCAAAACGCCGTAAGaccggaaagc
|
2753489 | 2753503 | [ICA] | [5] | |
CpxR-phosphorylated | activator | cpxPp | Sigma70 | -52.0 | -87.0 | cpxP, cpxQ |
aatccatgacTTTACGTTGTTTTACaccccctgac
|
4105726 | 4105740 | [GEA], [APIORCISFBSCS], [BPP] | [3], [6], [7] | |
CpxR-phosphorylated | activator | cpxPp | Sigma70 | -32.0 | -67.0 | cpxP, cpxQ |
tttacaccccCTGACGCATGTTTGCagcctgaatc
|
4105746 | 4105760 | [APIORCISFBSCS], [GEA], [APIORCISFBSCS] | [6], [7] | |
CpxR-phosphorylated | activator | cpxPp | Sigma70 | -5.0 | -40.0 | cpxP, cpxQ |
agcctgaatcGTAAACTCTCTATCGTTGAAtcgcgacaga
|
4105771 | 4105790 | [GEA], [APIORCISFBSCS], [BPP] | [3], [6], [7] | |
CpxR-phosphorylated | activator | cpxRp | Sigma70 | -67.0 | -83.0 | cpxR, cpxA |
gattcaggctGCAAACATGCGTCAGggggtgtaaa
|
4105746 | 4105760 | [GEA], [APIORCISFBSCS] | [6], [7] | |
CpxR-phosphorylated | activator | cpxRp | Sigma70 | -47.0 | -63.0 | cpxR, cpxA |
gtcagggggtGTAAAACAACGTAAAgtcatggatt
|
4105726 | 4105740 | [GEA], [APIORCISFBSCS], [BPP] | [6], [7] | |
CpxR-phosphorylated | activator | cpxRp2 | Sigma38 | -67.0 | -83.0 | cpxR, cpxA |
gattcaggctGCAAACATGCGTCAGggggtgtaaa
|
4105746 | 4105760 | [GEA], [APIORCISFBSCS] | [6], [7] | |
CpxR-phosphorylated | activator | cpxRp2 | Sigma38 | -47.0 | -63.0 | cpxR, cpxA |
gtcagggggtGTAAAACAACGTAAAgtcatggatt
|
4105726 | 4105740 | [GEA], [APIORCISFBSCS], [BPP] | [6], [7] | |
CpxR-phosphorylated | repressor | csgBp | Sigma70 | -464.0 | -556.0 | csgB, csgA, csgC |
gtgttaaacaTGTAACTAAATGTAActcgttatat
|
1103388 | 1103402 | [GEA], [APIORCISFBSCS], [BPP] | [8] | |
CpxR-phosphorylated | repressor | csgBp | Sigma70 | -255.0 | -347.0 | csgB, csgA, csgC |
cacacctccgTGGACAATTTTTTACtgcaaaaaga
|
1103597 | 1103611 | [APIORCISFBSCS] | [5] | |
CpxR-phosphorylated | repressor | csgBp | Sigma70 | 8.0 | -85.0 | csgB, csgA, csgC |
actttccatcGTAACGCAGCGTTAAcaaaatacag
|
1103859 | 1103873 | [GEA], [AIBSCS], [APIORCISFBSCS], [BPP] | [5], [8] | |
CpxR-phosphorylated | repressor | csgBp2 | Sigma38 | -464.0 | -556.0 | csgB, csgA, csgC |
gtgttaaacaTGTAACTAAATGTAActcgttatat
|
1103388 | 1103402 | [GEA], [APIORCISFBSCS], [BPP] | [8] | |
CpxR-phosphorylated | repressor | csgBp2 | Sigma38 | -255.0 | -347.0 | csgB, csgA, csgC |
cacacctccgTGGACAATTTTTTACtgcaaaaaga
|
1103597 | 1103611 | [APIORCISFBSCS] | [5] | |
CpxR-phosphorylated | repressor | csgBp2 | Sigma38 | 8.0 | -85.0 | csgB, csgA, csgC |
actttccatcGTAACGCAGCGTTAAcaaaatacag
|
1103859 | 1103873 | [GEA], [AIBSCS], [APIORCISFBSCS], [BPP] | [5], [8] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -186.0 | -334.0 | csgD, csgE, csgF, csgG |
accgaaatatTTTTTATATGCATTAttagtaagtt
|
1103523 | 1103537 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -178.0 | -326.0 | csgD, csgE, csgF, csgG |
attttttataTGCATTATTAGTAAgttatcacca
|
1103516 | 1103529 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -166.0 | -314.0 | csgD, csgE, csgF, csgG |
cattattagtAAGTTATCACCATTTgtatgatttt
|
1103503 | 1103517 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -141.0 | -289.0 | csgD, csgE, csgF, csgG |
gtatgattttTTAAAATTGTGCAATaaaaaccaaa
|
1103478 | 1103492 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -129.5 | -277.5 | csgD, csgE, csgF, csgG |
ttaaaattgtGCAATAAAAACCAAATGtacaactttt
|
1103466 | 1103482 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -108.5 | -256.5 | csgD, csgE, csgF, csgG |
aaatgtacaaCTTTTCTATCATTTCtaaacttaat
|
1103446 | 1103460 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -100.0 | -248.0 | csgD, csgE, csgF, csgG |
acttttctatCATTTCTAAACTTAAtaaaacctta
|
1103437 | 1103451 | [GEA], [APIORCISFBSCS], [BPP] | [9], [10] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -95.5 | -243.5 | csgD, csgE, csgF, csgG |
ttctatcattTCTAAACTTAATAAAaccttaaggt
|
1103433 | 1103447 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -73.5 | -221.5 | csgD, csgE, csgF, csgG |
aaaaccttaaGGTTAACATTTTAATataacgagtt
|
1103411 | 1103425 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -52.0 | -200.0 | csgD, csgE, csgF, csgG |
aatataacgaGTTACATTTAGTTACatgtttaaca
|
1103389 | 1103403 | [GEA], [APIORCISFBSCS], [BPP] | [8], [10] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -48.0 | -196.0 | csgD, csgE, csgF, csgG |
taacgagttaCATTTAGTTACATGTttaacacttg
|
1103385 | 1103399 | [GEA], [APIORCISFBSCS], [BPP] | [10] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -43.0 | -191.0 | csgD, csgE, csgF, csgG |
agttacatttAGTTACATGTTTAACacttgattta
|
1103380 | 1103394 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | -21.5 | -169.5 | csgD, csgE, csgF, csgG |
taacacttgaTTTAAGATTTGTAATggctagattg
|
1103359 | 1103373 | [GEA], [APIORCISFBSCS], [BPP] | [9], [10] | |
CpxR-phosphorylated | repressor | csgDp1 | Sigma70 | 3.0 | -146.0 | csgD, csgE, csgF, csgG |
tggctagattGAAATCAGATGTAATccattagttt
|
1103335 | 1103349 | [GEA], [APIORCISFBSCS], [BPP] | [10] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -186.0 | -334.0 | csgD, csgE, csgF, csgG |
accgaaatatTTTTTATATGCATTAttagtaagtt
|
1103523 | 1103537 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -178.0 | -326.0 | csgD, csgE, csgF, csgG |
attttttataTGCATTATTAGTAAgttatcacca
|
1103516 | 1103529 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -166.0 | -314.0 | csgD, csgE, csgF, csgG |
cattattagtAAGTTATCACCATTTgtatgatttt
|
1103503 | 1103517 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -141.0 | -289.0 | csgD, csgE, csgF, csgG |
gtatgattttTTAAAATTGTGCAATaaaaaccaaa
|
1103478 | 1103492 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -129.5 | -277.5 | csgD, csgE, csgF, csgG |
ttaaaattgtGCAATAAAAACCAAATGtacaactttt
|
1103466 | 1103482 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -108.5 | -256.5 | csgD, csgE, csgF, csgG |
aaatgtacaaCTTTTCTATCATTTCtaaacttaat
|
1103446 | 1103460 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -100.0 | -248.0 | csgD, csgE, csgF, csgG |
acttttctatCATTTCTAAACTTAAtaaaacctta
|
1103437 | 1103451 | [GEA], [APIORCISFBSCS], [BPP] | [9], [10] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -95.5 | -243.5 | csgD, csgE, csgF, csgG |
ttctatcattTCTAAACTTAATAAAaccttaaggt
|
1103433 | 1103447 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -73.5 | -221.5 | csgD, csgE, csgF, csgG |
aaaaccttaaGGTTAACATTTTAATataacgagtt
|
1103411 | 1103425 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -52.0 | -200.0 | csgD, csgE, csgF, csgG |
aatataacgaGTTACATTTAGTTACatgtttaaca
|
1103389 | 1103403 | [GEA], [APIORCISFBSCS], [BPP] | [8], [10] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -48.0 | -196.0 | csgD, csgE, csgF, csgG |
taacgagttaCATTTAGTTACATGTttaacacttg
|
1103385 | 1103399 | [GEA], [APIORCISFBSCS], [BPP] | [10] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -43.0 | -191.0 | csgD, csgE, csgF, csgG |
agttacatttAGTTACATGTTTAACacttgattta
|
1103380 | 1103394 | [GEA], [APIORCISFBSCS], [BPP] | [9] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | -21.5 | -169.5 | csgD, csgE, csgF, csgG |
taacacttgaTTTAAGATTTGTAATggctagattg
|
1103359 | 1103373 | [GEA], [APIORCISFBSCS], [BPP] | [9], [10] | |
CpxR-phosphorylated | repressor | csgDp3 | Sigma38 | 3.0 | -146.0 | csgD, csgE, csgF, csgG |
tggctagattGAAATCAGATGTAATccattagttt
|
1103335 | 1103349 | [GEA], [APIORCISFBSCS], [BPP] | [10] | |
CpxR-phosphorylated | repressor | cyaRp | Sigma70 | nd | nd | cyaR | nd | nd | [GEA], [BPP] | [11] | ||
CpxR-phosphorylated | repressor | cyaRp2 | Sigma24 | nd | nd | cyaR | nd | nd | [GEA], [BPP] | [11] | ||
CpxR-phosphorylated | repressor | cyaRp3 | Sigma38 | nd | nd | cyaR | nd | nd | [GEA], [BPP] | [11] | ||
CpxR-phosphorylated | activator | degPp | Sigma24 | -223.0 | -262.0 | degP |
gaggctgtcaGTAAATTACCGTCAGattctcctga
|
180615 | 180629 | [GEA], [BPP] | [1], [12] | |
CpxR-phosphorylated | activator | degPp | Sigma24 | -71.5 | -110.5 | degP |
ccaggcttttGTAAAGACGAACAATAAATttttaccttt
|
180765 | 180783 | [GEA], [AIBSCS], [APIORCISFBSCS], [BPP] | [1], [3], [12] | |
CpxR-phosphorylated | activator | degPp | Sigma24 | -63.0 | -102.0 | degP |
gtaaagacgaACAATAAATTTTTACcttttgcaga
|
180775 | 180789 | [GEA], [APIORCISFBSCS], [BPP] | [1], [12] | |
CpxR-phosphorylated | activator | dgcZp | Sigma70 | -41.0 | -70.0 | dgcZ |
aacttcggatTTCTATGAAAATATTGACgtaattttgc
|
1623912 | 1623929 | [GEA], [APIORCISFBSCS], [BPP] | [3], [7] | |
CpxR-phosphorylated | activator | dsbCp | Sigma24 | -391.5 | -403.5 | dsbC |
acgggtcattGGTAAAGGCAACAAAgagcgtctgg
|
3039219 | 3039233 | [GEA], [APIORCISFBSCS] | [13] | |
CpxR-phosphorylated | activator | dsbCp | Sigma24 | -357.5 | -369.5 | dsbC |
tgccgttaggTGAAGAGGCGGTTTActggctggaa
|
3039184 | 3039198 | [GEA], [APIORCISFBSCS] | [13] | |
CpxR-phosphorylated | repressor | efeUp | Sigma70 | -54.5 | -103.5 | efeU |
ccaacatcatTTTATAAACATTCCGcttgtgtttt
|
1081246 | 1081260 | [GEA], [APIORCISFBSCS], [BPP] | [3], [7] | |
CpxR-phosphorylated | activator | ftnBp2 | Sigma70 | -61.0 | -187.0 | ftnB |
tcaatgaaatGTAAAAATATATAAActtgatgatt
|
1986731 | 1986745 | [APIORCISFBSCS], [BPP] | [3] | |
CpxR-phosphorylated | activator | hlpAp | Sigma24 | -101.0 | -128.0 | skp, lpxD, fabZ, lpxA |
tttaacatcgGTAAAACCTGGTAAGtgttctccac
|
200347 | 200361 | [GEA], [APIORCISFBSCS] | [13] | |
CpxR-phosphorylated | activator | ldtCp | Sigma70 | -53.5 | -96.5 | ldtC |
catctgcaacATTTACAAATTCTTTGCacttccctgc
|
1170463 | 1170479 | [APIORCISFBSCS], [BPP] | [3] | |
CpxR-phosphorylated | activator | ldtDp | nd | -192.0 | -308.0 | ldtD |
gatttgcgccGCAACTCCCTGAAACGcttccaggaa
|
980732 | 980747 | [GEA], [APIORCISFBSCS], [BPP] | [7], [14] | |
CpxR-phosphorylated | activator | marRp | Sigma70 | -29.0 | -56.0 | marR, marA, marB |
attcattcatTTGACTTATACTTGCCtgggcaatat
|
1619057 | 1619072 | [GEA], [APIORCISFBSCS], [BPP] | [15] | |
CpxR-phosphorylated | activator | mdtAp | Sigma38 | -128.5 | -165.5 | mdtA, mdtB, mdtC, mdtD, baeS, baeR |
cagtctatcgCTAACGCGTAGATAAAAtagtttcctg
|
2153843 | 2153859 | [GEA], [IC], [BPP], [IC] | [4] | |
CpxR-phosphorylated | activator | mdtAp | Sigma38 | -66.5 | -103.5 | mdtA, mdtB, mdtC, mdtD, baeS, baeR |
atgtgcccgtCATTCAGACGATTCCagacagtgtt
|
2153906 | 2153920 | [GEA], [IC], [BPP], [IC] | [4] | |
CpxR-phosphorylated | repressor | motAp | Sigma28 | -37.0 | -200.0 | motA, motB, cheA, cheW |
atcccgggcaGTAAAAAGACGTAAActttcccaga
|
1977332 | 1977346 | [GEA], [BPP] | [5], [6] | |
CpxR-phosphorylated | activator | ompCp1 | Sigma70 | -351.0 | -432.0 | ompC |
tgaaaagtgtGTAAAGAAGGGTAAAaaaaaccgaa
|
2313174 | 2313188 | [GEA], [AIBSCS], [BPP] | [16] | |
CpxR-phosphorylated | activator | ompCp1 | Sigma70 | -134.0 | -215.0 | ompC |
atgttaggtgCTTATTTCGCCATTCcgcaataatc
|
2312957 | 2312971 | [GEA], [AIBSCS], [BPP] | [16] | |
CpxR-phosphorylated | activator | ompCp1 | Sigma70 | -95.0 | -176.0 | ompC |
aagttcccttGCATTTACATTTtgaaacatct
|
2312920 | 2312931 | [GEA], [AIBSCS], [BPP] | [16] | |
CpxR-phosphorylated | repressor | ompFp | Sigma70 | -429.5 | -539.5 | ompF |
ttttctgtcaAGTTATCTGTTTGTTAAgtcaagcaat
|
987514 | 987530 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | repressor | ompFp | Sigma70 | -373.0 | -483.0 | ompF |
cgatcatcctGTTACGGAATATTACattgcaacat
|
987458 | 987472 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | repressor | ompFp | Sigma70 | -93.0 | -203.0 | ompF |
ttccttaaatTTTACTTTTGGTTACatattttttc
|
987178 | 987192 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | repressor | ompFp | Sigma70 | -68.5 | -178.5 | ompF |
acatatttttTCTTTTTGAAACCAAATctttatcttt
|
987153 | 987169 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | repressor | ompFp2 | Sigma38 | -429.5 | -539.5 | ompF |
ttttctgtcaAGTTATCTGTTTGTTAAgtcaagcaat
|
987514 | 987530 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | repressor | ompFp2 | Sigma38 | -373.0 | -483.0 | ompF |
cgatcatcctGTTACGGAATATTACattgcaacat
|
987458 | 987472 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | repressor | ompFp2 | Sigma38 | -93.0 | -203.0 | ompF |
ttccttaaatTTTACTTTTGGTTACatattttttc
|
987178 | 987192 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | repressor | ompFp2 | Sigma38 | -68.5 | -178.5 | ompF |
acatatttttTCTTTTTGAAACCAAATctttatcttt
|
987153 | 987169 | [GEA], [AIBSCS], [BPP] | [7], [16] | |
CpxR-phosphorylated | activator | ppiAp1 | Sigma70 | -47.0 | -85.0 | ppiA |
tttcagatacGTAAAATTAGGTAAAgggatggcct
|
3492375 | 3492389 | [GEA], [APIORCISFBSCS], [BPP] | [1], [3], [17] | |
CpxR-phosphorylated | activator | ppiDp2 | Sigma70 | -165.0 | -261.0 | ppiD |
ccgcagaccgGTAAAGAGATCACCAtcgctgctgc
|
461647 | 461661 | [APIORCISFBSCS], [SM] | [18] | |
CpxR-phosphorylated | activator | ppiDp2 | Sigma70 | -117.0 | -213.0 | ppiD |
ttccgtgcagGTAAAGCACTGAAAGacgcggtaaa
|
461695 | 461709 | [APIORCISFBSCS], [SM] | [18] | |
CpxR-phosphorylated | activator | ppiDp2 | Sigma70 | -96.5 | -192.5 | ppiD |
gaaagacgcgGTAAACTAAGCGTTGTCcccagtgggg
|
461715 | 461731 | [APIORCISFBSCS], [SM] | [18] | |
CpxR-phosphorylated | repressor | psdp | Sigma24 | 151.0 | -128.0 | psd, mscM |
catggcgcagGTAAAAACGCGTAAAaacttttctg
|
4390481 | 4390495 | [ICA] | [5] | |
CpxR-phosphorylated | repressor | rpoEp1a | nd | 67.0 | 45.0 | rseD, rpoE, rseA, rseB, rseC |
aaacagatgcGTTACGGAACTTTACaaaaacgaga
|
2710113 | 2710127 | [GEA], [AIBSCS] | [5] | |
CpxR-phosphorylated | activator | rpoHp1 | Sigma70 | nd | nd | rpoH | nd | nd | [GEA], [BPP] | [19] | ||
CpxR-phosphorylated | activator | rpoHp2 | Sigma38 | nd | nd | rpoH | nd | nd | [GEA], [BPP] | [19] | ||
CpxR-phosphorylated | activator | rprAp | nd | nd | nd | rprA | nd | nd | [GEA], [BPP] | [11] | ||
CpxR-phosphorylated | activator | sbmAp | Sigma24 | nd | nd | sbmA, yaiW | nd | nd | [GEA], [BPP] | [7] | ||
CpxR-phosphorylated | activator | sltp7 | Sigma32 | -52.0 | -85.0 | slt |
aaaagtgtccGTAACGTGGCGTAAACggcaatgact
|
4630641 | 4630656 | [GEA], [IGI], [AIBSCS], [APIORCISFBSCS], [BPP] | [7], [14] | |
CpxR-phosphorylated | activator | spyp | Sigma70 | -50.0 | -113.0 | spy |
gttttttacaCTTTCATTGTTTTACcgttgctctg
|
1825731 | 1825745 | [GEA], [APIORCISFBSCS], [BPP] | [3], [7], [20], [21] | |
CpxR-phosphorylated | activator | srkAp | Sigma70 | -49.0 | -73.0 | srkA, dsbA |
taattaaagaGTAAAAGCTTGTAAGcggcgccacc
|
4042335 | 4042349 | [GEA], [APIORCISFBSCS], [BPP] | [1], [3], [22] | |
CpxR-phosphorylated | activator | tomBp | Sigma70 | -50.0 | -136.0 | tomB, hha |
cttcctaattGTAATTTTTCGTAATaatgcgatga
|
480837 | 480851 | [APIORCISFBSCS], [BPP] | [3] | |
CpxR-phosphorylated | repressor | tsrp1 | Sigma70 | -9.0 | -254.0 | tsr |
ttacgcgcgcGTAAAGTAAGGTAAAtaactgagtg
|
4591396 | 4591410 | [BPP] | [6] | |
CpxR-phosphorylated | repressor | ungp | nd | -81.0 | -97.0 | ung |
attttaccaaTTTACATTTTTTTGCactcgtttaa
|
2716650 | 2716664 | [BCE], [BPP] | [23] | |
CpxR-phosphorylated | activator | yccAp | Sigma70 | -53.0 | -78.0 | yccA |
gatcaaatgcGTAAAGATGGGTAAAacttctgggt
|
1031489 | 1031503 | [GEA], [APIORCISFBSCS], [BPP] | [3], [7] | |
CpxR-phosphorylated | activator | yebEp | Sigma70 | -44.0 | -69.0 | yebE |
ttgcgcatctTTTGTCTCGATATACattttctgac
|
1929769 | 1929783 | [GEA], [APIORCISFBSCS], [BPP] | [3], [7] | |
CpxR-phosphorylated | activator | yidQp | Sigma24 | -254.0 | -438.0 | yidQ |
tagcaatgcgGTAATGGTTTTCGTCTACcagttcaacg
|
3867282 | 3867299 | [GEA], [APIORCISFBSCS] | [13] | |
CpxR-phosphorylated | activator | yidQp | Sigma24 | -176.0 | -360.0 | yidQ |
tttctaagtgGTTAAACAAACGGTCAAAtccaatagca
|
3867360 | 3867377 | [GEA], [APIORCISFBSCS] | [13] | |
CpxR-phosphorylated | activator | yidQp | Sigma24 | -143.5 | -327.5 | yidQ |
tagcagaacgGTAAAGCGGGGATAAATcaaagttacg
|
3867393 | 3867409 | [GEA], [APIORCISFBSCS] | [13] | |
CpxR-phosphorylated | activator | yqaEp | nd | -48.0 | -105.0 | yqaE, kbp |
gcctcagcagCGTAAATGAGAGTAAAagcgtaagct
|
2797126 | 2797141 | [GEA], [AIBSCS], [APIORCISFBSCS], [BPP] | [7], [11], [14] | |
CpxR-phosphorylated | activator | yqjAp1 | Sigma70 | -47.0 | -272.0 | yqjA, mzrA |
agtataaagtGTCAGCCTGTGTAAAtcctctcgcc
|
3247494 | 3247508 | [APIORCISFBSCS], [BPP] | [3] |
Alignment and PSSM for CpxR TFBSs | ![]() |
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Aligned TFBS of CpxR |
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Sequence | |
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TTTACGTTGTTTTACACCCC | |
TTTACGTCTTTTTACTGCCC | |
TTTACCCATCTTTACGCATT | |
TTTTCGCCGCTTTACGGTTA | |
TTTACCCTTCTTTACACACT | |
CTTTCATTGTTTTACCGTTG | |
TTTACATTTTTTTGCACTCG | |
CTTACCAGGTTTTACCGATG | |
TTTACGCCACGTTACGGACA | |
TTTACCTTACTTTACGCGCG | |
TTTACCTAATTTTACGTATC | |
TTTACGCGTTTTTACCTGCG | |
CTTACGGCGTTTTGCTGTTT | |
TTATCCCCGCTTTACCGTTC | |
TTTACTTTTGGTTACATATT | |
CTTACAAGCTTTTACTCTTT | |
TTTATATATTTTTACATTTC | |
CTTTCAGTGCTTTACCTGCA | |
TTAACGCTGCGTTACGATGG | |
TTTACACAGGCTGACACTTT | |
CTGACGGTAATTTACTGACA | |
CTGACGCATGTTTGCAGCCT | |
TTTACTCTCATTTACGCTGC | |
GTTACGGAACTTTACAAAAA | |
TGGACAATTTTTTACTGCAA | |
TAAACGGGGTTTTACACTAT | |
ATTACGAAAAATTACAATTA | |
TTTACAAATTCTTTGCACTT | |
TTATCTACGCGTTAGCGATA | |
GTTACGGAATATTACATTGC | |
ATTACATCTGATTTCAATCT | |
CTTTGTTGCCTTTACCAATG | |
TGTACATTTGGTTTTTATTG | |
TGGTGATCTCTTTACCGGTC | |
TTTTATTAAGTTTAGAAATG | |
TTTTCTTTTTGAAACCAAAT | |
TTGACCGTTTGTTTAACCAC | |
ATTACATTAACTGACTTTCC | |
TTGACTTATACTTGCCTGGG | |
TTTAAGATTTGTAATGGCTA | |
TTTTATAAACATTCCGCTTG | |
GTTTCAGGGAGTTGCGGCGC | |
TGTAAATTATCATGCCCTTT | |
CTTTTGTCTCGATATACATT | |
CGATAGAGAGTTTACGATTC | |
CTTTTCTATCATTTCTAAAC | |
TTATCTGTTTGTTAAGTCAA | |
CTTATTTCGCCATTCCGCAA | |
ATTGTTCGTCTTTACAAAAG | |
TAAACTAAGCGTTGTCCCCA | |
CTGACCAAAGAATACTTGCA | |
AGTTACATGTTTAACACTTG | |
ATTACGTCAATATTTTCATA | |
CATACAAATGGTGATAACTT | |
TATTAAAATGTTAACCTTAA | |
TATATGCATTATTAGTAAGT | |
CGGTAATGGTTTTCGTCTAC | |
CTTGCATTTACATTTTGAAA | |
CTGGAATCGTCTGAATGACG | |
TAAACCGCCTCTTCACCTAA |
Position weight matrix (PWM). CpxR matrix-quality result |
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A 6 6 8 39 9 19 14 18 14 8 7 7 4 42 4 18 14 19 13 17 C 17 0 0 0 43 11 12 13 4 18 9 0 0 3 44 16 18 12 15 14 G 3 7 9 3 2 18 10 9 17 10 13 0 4 7 5 12 17 6 6 14 T 34 47 43 18 6 12 24 20 25 24 31 53 52 8 7 14 11 23 26 15 |
Consensus |
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; consensus.strict tttaCgtttctTTaCccttg ; consensus.strict.rc CAAGGGTAAAGAAACGTAAA ; consensus.IUPAC yttwCrthkykTTaCmswys ; consensus.IUPAC.rc SRWSKGTAAMRMDAYGWAAR ; consensus.regexp [ct]tt[at]C[ag]t[act][gt][ct][gt]TTaC[ac][cg][at][ct][cg] ; consensus.regexp.rc [CG][AG][AT][CG][GT]GTAA[AC][AG][AC][AGT]A[CT]G[AT]AA[AG] |
Evolutionary conservation of regulatory elements | ![]() |
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Reference(s) |
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