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Synonyms: NarL-phosphorylated, NarL |
Summary:
NarL, "nitrate/nitrite response regulator NarL," is a transcriptional dual regulator of many anaerobic electron transport and fermentation-related genes in the response to the availability of high concentrations of nitrate or nitrite [45, 46]. NarL activates expression of 51 operons in response to nitrate, mostly genes needed for nitrate respiration. NarL represses 41 operons involved in alternative respiratory pathways, such as fumarate reduction or fermentation of simple sugars [47]. The response regulator NarL belongs to the LuxR/UhpA family [48, 49] and is part of the two-component system NarX-NarL. There is intensive cross-regulation with the paralogous two-component system NarQ-NarP [14, 50]. Each of the sensors, NarX and NarQ, is able to phosphorylate NarL and NarP, leading to the activation of both proteins. In the absence of nitrate and nitrite, NarX and NarQ stimulate the dephosphorylation of NarL-P and NarP-P [51, 52]. Read more > |
Transcription factor | ![]() ![]() |
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TF conformation(s): |
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Evolutionary Family: | LuxR/UhpA | ||||||||||||||||||
Sensing class: | External-Two-component systems | ||||||||||||||||||
Connectivity class: | Local Regulator | ||||||||||||||||||
Gene name: | narL | ||||||||||||||||||
Genome position: | 1275179-1275829 | ||||||||||||||||||
Length: | 651 bp / 216 aa | ||||||||||||||||||
Operon name: | narXL | ||||||||||||||||||
TU(s) encoding the TF: |
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Transcription factor regulation |
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Functional conformation | Function | Promoter | Sigma factor | Central Rel-Pos | Distance to first Gene | Genes | Sequence | LeftPos | RightPos | Evidence (Confirmed, Strong, Weak) | References | |
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NarL-phosphorylated | repressor | adhEp | Sigma38 | 81.0 | -212.0 | adhE |
acgtaatcagTACCCAGaagtgagtaa
|
1298330 | 1298336 | [GEA], [APIORCISFBSCS] | [2], [3] | |
NarL-phosphorylated | repressor | adhEp | Sigma38 | 90.0 | -203.0 | adhE |
gtacccagaaGTGAGTAatcttgctta
|
1298321 | 1298327 | [GEA], [APIORCISFBSCS] | [2], [3] | |
NarL-phosphorylated | repressor | adhEp1 | Sigma70 | 81.0 | -212.0 | adhE |
acgtaatcagTACCCAGaagtgagtaa
|
1298330 | 1298336 | [GEA], [APIORCISFBSCS] | [2], [3] | |
NarL-phosphorylated | repressor | adhEp1 | Sigma70 | 90.0 | -203.0 | adhE |
gtacccagaaGTGAGTAatcttgctta
|
1298321 | 1298327 | [GEA], [APIORCISFBSCS] | [2], [3] | |
NarL-phosphorylated | repressor | adhEp2 | Sigma38 | -24.0 | -212.0 | adhE |
acgtaatcagTACCCAGaagtgagtaa
|
1298330 | 1298336 | [GEA], [APIORCISFBSCS] | [3] | |
NarL-phosphorylated | repressor | adhEp2 | Sigma38 | -15.0 | -203.0 | adhE |
gtacccagaaGTGAGTAatcttgctta
|
1298321 | 1298327 | [GEA], [APIORCISFBSCS] | [3] | |
NarL-phosphorylated | repressor | aspAp | Sigma70 | -112.0 | -217.0 | aspA, dcuA |
aactatttttGGTAGTAatcccaaagc
|
4368541 | 4368547 | [GEA], [BPP] | [4] | |
NarL-phosphorylated | repressor | aspAp | Sigma70 | -76.0 | -181.0 | aspA, dcuA |
tttcacaaatTAATAATtaaggggtaa
|
4368505 | 4368511 | [GEA], [BPP] | [4] | |
NarL-phosphorylated | repressor | aspAp | Sigma70 | -67.0 | -172.0 | aspA, dcuA |
ttaataattaAGGGGTAaaaaccgaca
|
4368496 | 4368502 | [GEA], [BPP] | [4] | |
NarL-phosphorylated | repressor | caiFp | Sigma70 | nd | nd | caiF | nd | nd | [GEA], [BPP] | [5] | ||
NarL-phosphorylated | repressor | citCp2 | nd | 37.0 | -147.0 | citC, citD, citE, citF, citX, citG |
tcacgccgaaATACTCCTtaggatgtat
|
652000 | 652007 | [AIBSCS], [AIBSCS] | [6] | |
NarL-phosphorylated | activator | cydDp | Sigma70 | -126.0 | -195.0 | cydD, cydC |
gccaggccatTACTTCGgccggtacag
|
931154 | 931160 | [GEA], [APIORCISFBSCS] | [7] | |
NarL-phosphorylated | activator | cydDp | Sigma70 | -80.0 | -149.0 | cydD, cydC |
tgcggaacgcTACCTCGatggtttagc
|
931108 | 931114 | [GEA], [APIORCISFBSCS] | [7] | |
NarL-phosphorylated | repressor | dcuBp1 | Sigma70 | -109.0 | -129.0 | dcuB, fumB |
atattcactgTGAGGTAtttgctaaag
|
4348870 | 4348876 | [GEA], [APIORCISFBSCS] | [8] | |
NarL-phosphorylated | repressor | dcuBp1 | Sigma70 | -45.0 | -65.0 | dcuB, fumB |
aaacagttcaTACAAAAcagaacgtga
|
4348806 | 4348812 | [GEA], [APIORCISFBSCS] | [8] | |
NarL-phosphorylated | repressor | dcuBp1 | Sigma70 | 2.0 | -19.0 | dcuB, fumB |
aatttaaataGGATTATcgcgagggtt
|
4348760 | 4348766 | [GEA], [APIORCISFBSCS] | [8] | |
NarL-phosphorylated | repressor | dcuBp1 | Sigma70 | 19.0 | -2.0 | dcuB, fumB |
cgcgagggttCACACATgttatttact
|
4348743 | 4348749 | [GEA], [APIORCISFBSCS] | [8] | |
NarL-phosphorylated | repressor | dcuBp1 | Sigma70 | 24.0 | 4.0 | dcuB, fumB |
gggttcacacATGTTATttactatcca
|
4348738 | 4348744 | [GEA], [APIORCISFBSCS] | [8] | |
NarL-phosphorylated | repressor | dcuBp1 | Sigma70 | 43.0 | 23.0 | dcuB, fumB |
actatccaacTTATCATaatactgata
|
4348719 | 4348725 | [GEA], [APIORCISFBSCS] | [8] | |
NarL-phosphorylated | repressor | dcuSp | Sigma70 | -40.0 | -63.0 | dcuS, dcuR |
caatcattctTACTCCCtttgaattac
|
4351722 | 4351728 | [GEA], [APIORCISFBSCS], [BPP] | [4] | |
NarL-phosphorylated | repressor | dcuSp | Sigma70 | -31.0 | -54.0 | dcuS, dcuR |
ttactcccttTGAATTAcccgcctcat
|
4351713 | 4351719 | [GEA], [APIORCISFBSCS], [BPP] | [4] | |
NarL-phosphorylated | repressor | dmsAp1 | Sigma70 | -27.0 | -163.0 | dmsA, dmsB, dmsC |
gaacaataatTACTCCTcacttacacg
|
940793 | 940799 | [BCE], [BPP] | [9] | |
NarL-phosphorylated | repressor | dmsAp1 | Sigma70 | -7.0 | -143.0 | dmsA, dmsB, dmsC |
ttacacgtaaTACTACTttcgagtgaa
|
940813 | 940819 | [BCE], [BPP] | [9] | |
NarL-phosphorylated | repressor | dmsAp1 | Sigma70 | 15.0 | -122.0 | dmsA, dmsB, dmsC |
agtgaaaatcTACCTATctctttgatt
|
940834 | 940840 | [APIORCISFBSCS], [BPP] | [9] | |
NarL-phosphorylated | repressor | dpiBp1 | nd | 20.0 | -232.0 | dpiB, dpiA |
atacatcctaAGGAGTATttcggcgtga
|
652000 | 652007 | [AIBSCS] | [6] | |
NarL-phosphorylated | repressor | dpiBp2 | nd | 25.0 | -39.0 | dpiB, dpiA |
acattttaatTACATCCGtcaaagaggc
|
652193 | 652200 | [AIBSCS] | [6] | |
NarL-phosphorylated | repressor | fdhFp | Sigma54 | nd | nd | fdhF | nd | nd | [GEA], [BPP] | [10] | ||
NarL-phosphorylated | activator | fdnGp | Sigma70 | -124.0 | -153.0 | fdnG, fdnH, fdnI |
cctgtcaggcAGTGGTGcgtttttcta
|
1547245 | 1547251 | [GEA], [APIORCISFBSCS], [BCE], [SM] | [10], [11], [12], [13], [14] | |
NarL-phosphorylated | activator | fdnGp | Sigma70 | -109.0 | -138.0 | fdnG, fdnH, fdnI |
tgcgtttttcTACCGCTattgaggtag
|
1547260 | 1547266 | [GEA], [BCE], [SM] | [10], [15] | |
NarL-phosphorylated | activator | fdnGp | Sigma70 | -100.0 | -129.0 | fdnG, fdnH, fdnI |
ctaccgctatTGAGGTAggtcaatttg
|
1547269 | 1547275 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [10], [11], [12], [14] | |
NarL-phosphorylated | activator | fdnGp | Sigma70 | -77.0 | -106.0 | fdnG, fdnH, fdnI |
tttgcgaaggCGGATTAttttgtggca
|
1547292 | 1547298 | [GEA], [APIORCISFBSCS], [BCE], [SM] | [10], [11], [12], [14] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -348.0 | -375.0 | focA, pflB |
aatgtaggctTAATGATtagtctgagt
|
954838 | 954844 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -346.0 | -373.0 | focA, pflB |
tgtaggcttaATGATTAgtctgagtta
|
954836 | 954842 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -286.0 | -313.0 | focA, pflB |
catatatttgCATTAATaaaataattg
|
954776 | 954782 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -270.0 | -297.0 | focA, pflB |
taaaataattGTAATTAtaaggttaaa
|
954760 | 954766 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -253.0 | -280.0 | focA, pflB |
taaggttaaaTATCGGTaatttgtatt
|
954743 | 954749 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -235.0 | -262.0 | focA, pflB |
atttgtatttAATAAATacgatcgata
|
954725 | 954731 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -226.0 | -253.0 | focA, pflB |
taataaatacGATCGATattgttactt
|
954716 | 954722 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -152.0 | -179.0 | focA, pflB |
ggaaaaaattCAACTCAtttgttaatt
|
954642 | 954648 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -101.0 | -128.0 | focA, pflB |
aatcaaatatTTACTCCgtatttgcat
|
954591 | 954597 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -37.0 | -64.0 | focA, pflB |
gatatgatctATATCAAtttctcatct
|
954527 | 954533 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp1 | Sigma70 | -20.0 | -47.0 | focA, pflB |
tttctcatctATAATGCtttgttagta
|
954510 | 954516 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | -27.0 | -375.0 | focA, pflB |
aatgtaggctTAATGATtagtctgagt
|
954838 | 954844 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | -25.0 | -373.0 | focA, pflB |
tgtaggcttaATGATTAgtctgagtta
|
954836 | 954842 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 36.0 | -313.0 | focA, pflB |
catatatttgCATTAATaaaataattg
|
954776 | 954782 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 52.0 | -297.0 | focA, pflB |
taaaataattGTAATTAtaaggttaaa
|
954760 | 954766 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 69.0 | -280.0 | focA, pflB |
taaggttaaaTATCGGTaatttgtatt
|
954743 | 954749 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 87.0 | -262.0 | focA, pflB |
atttgtatttAATAAATacgatcgata
|
954725 | 954731 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 96.0 | -253.0 | focA, pflB |
taataaatacGATCGATattgttactt
|
954716 | 954722 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 170.0 | -179.0 | focA, pflB |
ggaaaaaattCAACTCAtttgttaatt
|
954642 | 954648 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 221.0 | -128.0 | focA, pflB |
aatcaaatatTTACTCCgtatttgcat
|
954591 | 954597 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 285.0 | -64.0 | focA, pflB |
gatatgatctATATCAAtttctcatct
|
954527 | 954533 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | focAp3 | Sigma70 | 302.0 | -47.0 | focA, pflB |
tttctcatctATAATGCtttgttagta
|
954510 | 954516 | [GEA], [APIORCISFBSCS], [BPP] | [16] | |
NarL-phosphorylated | repressor | frdAp | Sigma70 | -26.0 | -120.0 | frdA, frdB, frdC, frdD |
atttcagactTATCCATcagactatac
|
4382435 | 4382441 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp | Sigma70 | -12.0 | -106.0 | frdA, frdB, frdC, frdD |
catcagactaTACTGTTgtacctataa
|
4382421 | 4382427 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp | Sigma70 | -4.0 | -98.0 | frdA, frdB, frdC, frdD |
tatactgttgTACCTATaaaggagcag
|
4382413 | 4382419 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp | Sigma70 | 6.0 | -89.0 | frdA, frdB, frdC, frdD |
gtacctataaAGGAGCAgtggaatagc
|
4382404 | 4382410 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp | Sigma70 | 14.0 | -81.0 | frdA, frdB, frdC, frdD |
aaaggagcagTGGAATAgcgttcgcag
|
4382396 | 4382402 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp2 | Sigma38 | -26.0 | -120.0 | frdA, frdB, frdC, frdD |
atttcagactTATCCATcagactatac
|
4382435 | 4382441 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp2 | Sigma38 | -12.0 | -106.0 | frdA, frdB, frdC, frdD |
catcagactaTACTGTTgtacctataa
|
4382421 | 4382427 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp2 | Sigma38 | -4.0 | -98.0 | frdA, frdB, frdC, frdD |
tatactgttgTACCTATaaaggagcag
|
4382413 | 4382419 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp2 | Sigma38 | 6.0 | -89.0 | frdA, frdB, frdC, frdD |
gtacctataaAGGAGCAgtggaatagc
|
4382404 | 4382410 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | frdAp2 | Sigma38 | 14.0 | -81.0 | frdA, frdB, frdC, frdD |
aaaggagcagTGGAATAgcgttcgcag
|
4382396 | 4382402 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | hcpp1 | nd | -109.0 | -140.0 | hcp, hcr, poxB |
ctctgcgtaaTACCTCTctggcggtag
|
913951 | 913957 | [GEA], [APIORCISFBSCS], [BPP] | [17], [18] | |
NarL-phosphorylated | activator | hcpp1 | nd | -100.0 | -131.0 | hcp, hcr, poxB |
atacctctctGGCGGTAgatccctgcc
|
913942 | 913948 | [GEA], [APIORCISFBSCS], [BPP] | [17], [18] | |
NarL-phosphorylated | repressor | hyaAp | Sigma70 | -10.0 | -165.0 | hyaA, hyaB, hyaC, hyaD, hyaE, hyaF |
aaagtttcacTACGCTTtattaacaat
|
1031971 | 1031977 | [GEA], [APIORCISFBSCS] | ||
NarL-phosphorylated | repressor | hyaAp | Sigma70 | 7.0 | -149.0 | hyaA, hyaB, hyaC, hyaD, hyaE, hyaF |
ttattaacaaTACTTTCtggcgacgtg
|
1031987 | 1031993 | [GEA], [APIORCISFBSCS] | ||
NarL-phosphorylated | repressor | hyaAp2 | Sigma38 | -10.0 | -165.0 | hyaA, hyaB, hyaC, hyaD, hyaE, hyaF |
aaagtttcacTACGCTTtattaacaat
|
1031971 | 1031977 | [GEA], [APIORCISFBSCS] | ||
NarL-phosphorylated | repressor | hyaAp2 | Sigma38 | 7.0 | -149.0 | hyaA, hyaB, hyaC, hyaD, hyaE, hyaF |
ttattaacaaTACTTTCtggcgacgtg
|
1031987 | 1031993 | [GEA], [APIORCISFBSCS] | ||
NarL-phosphorylated | repressor | hybOp1 | Sigma70 | -76.0 | -178.0 | hybO, hybA, hybB, hybC, hybD, hybE, hybF, hybG |
tgatcaaacaTACGTATtatcttgctt
|
3146436 | 3146442 | [GEA], [APIORCISFBSCS] | [19] | |
NarL-phosphorylated | repressor | hybOp1 | Sigma70 | -51.0 | -153.0 | hybO, hybA, hybB, hybC, hybD, hybE, hybF, hybG |
tttaattaatTACACTAatgcttcttc
|
3146411 | 3146417 | [GEA], [APIORCISFBSCS] | [19] | |
NarL-phosphorylated | repressor | hybOp1 | Sigma70 | 21.0 | -82.0 | hybO, hybA, hybB, hybC, hybD, hybE, hybF, hybG |
ataataaatgTGTGGTAaatggcgcat
|
3146340 | 3146346 | [GEA], [APIORCISFBSCS] | [19] | |
NarL-phosphorylated | activator | moeAp | Sigma70 | -177.0 | -207.0 | moeA, moeB |
atgactgcttTGCCCATagtattcgtc
|
866568 | 866574 | [GEA], [AIBSCS] | [20] | |
NarL-phosphorylated | activator | moeAp | Sigma70 | -109.0 | -139.0 | moeA, moeB |
ttttatgaatTACTCATtcaatttttg
|
866500 | 866506 | [GEA], [AIBSCS] | [20] | |
NarL-phosphorylated | repressor | napFp1 | Sigma70 | -49.0 | -126.0 | napF, napD, napA, napG, napH, napB, napC, ccmA, ccmB, ccmC, ccmD, ccmE, ccmF, ccmG, ccmH |
ctacaggtttTACCCCGatcggggtat
|
2303620 | 2303626 | [GEA], [APIORCISFBSCS], [SM] | [21], [22], [23] | |
NarL-phosphorylated | repressor | napFp1 | Sigma70 | -40.0 | -117.0 | napF, napD, napA, napG, napH, napB, napC, ccmA, ccmB, ccmC, ccmD, ccmE, ccmF, ccmG, ccmH |
ttaccccgatCGGGGTAtgcatctttg
|
2303611 | 2303617 | [GEA], [APIORCISFBSCS], [SM] | [21], [22], [23] | |
NarL-phosphorylated | repressor | napFp2 | Sigma70 | -46.0 | -126.0 | napF, napD, napA, napG, napH, napB, napC, ccmA, ccmB, ccmC, ccmD, ccmE, ccmF, ccmG, ccmH |
ctacaggtttTACCCCGatcggggtat
|
2303620 | 2303626 | [GEA], [APIORCISFBSCS], [SM] | [23] | |
NarL-phosphorylated | repressor | napFp2 | Sigma70 | -37.0 | -117.0 | napF, napD, napA, napG, napH, napB, napC, ccmA, ccmB, ccmC, ccmD, ccmE, ccmF, ccmG, ccmH |
ttaccccgatCGGGGTAtgcatctttg
|
2303611 | 2303617 | [GEA], [APIORCISFBSCS], [SM] | [23] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -208.0 | -265.0 | narG, narH, narJ, narI |
attaatatgtTACCCATggggaatact
|
1279596 | 1279602 | [GEA], [APIORCISFBSCS], [BPP] | [13], [24], [25] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -195.0 | -252.0 | narG, narH, narJ, narI |
ccatggggaaTACTCCTtaatacccat
|
1279609 | 1279615 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [13], [24], [25], [26] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -185.0 | -242.0 | narG, narH, narJ, narI |
tactccttaaTACCCATctgcataaaa
|
1279619 | 1279625 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [13], [24], [25], [26] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -101.0 | -158.0 | narG, narH, narJ, narI |
tggtggctgtTAATTATcctaaagggg
|
1279703 | 1279709 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [12], [13], [14], [24], [25], [26] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -89.0 | -146.0 | narG, narH, narJ, narI |
attatcctaaAGGGGTAtcttaggaat
|
1279715 | 1279721 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [13], [24], [25], [26] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -79.0 | -136.0 | narG, narH, narJ, narI |
aggggtatctTAGGAATttactttatt
|
1279725 | 1279731 | [GEA], [APIORCISFBSCS], [BPP] | [13], [24], [25] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -71.0 | -128.0 | narG, narH, narJ, narI |
cttaggaattTACTTTAtttttcatcc
|
1279733 | 1279739 | [GEA], [APIORCISFBSCS], [BPP] | [13], [24], [25] | |
NarL-phosphorylated | activator | narGp | Sigma70 | -57.0 | -114.0 | narG, narH, narJ, narI |
ttatttttcaTCCCCATcactcttgat
|
1279747 | 1279753 | [GEA], [APIORCISFBSCS], [BPP] | [13], [24], [25] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -214.0 | -239.0 | narK |
ggctgaagtaTACCCATacccggaaag
|
1277715 | 1277721 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -194.0 | -219.0 | narK |
cggaaagagtTACTCCTtatttgccgt
|
1277735 | 1277741 | [APIORCISFBSCS], [BPP], [SM] | [13], [27] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -177.0 | -202.0 | narK |
tatttgccgtGTGGTTAgtcgctttac
|
1277752 | 1277758 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -160.0 | -185.0 | narK |
gtcgctttacATCGGTAagggtaggga
|
1277769 | 1277775 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -154.0 | -179.0 | narK |
ttacatcggtAAGGGTAgggattttac
|
1277775 | 1277781 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -103.0 | -128.0 | narK |
tttatgaagtCACTGTActcactatgg
|
1277826 | 1277832 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -98.0 | -123.0 | narK |
gaagtcactgTACTCACtatgggtaat
|
1277831 | 1277837 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -90.0 | -115.0 | narK |
tgtactcactATGGGTAatgataaata
|
1277839 | 1277845 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -80.0 | -105.0 | narK |
atgggtaatgATAAATAtcaatgatag
|
1277849 | 1277855 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | activator | narKp1 | Sigma70 | -67.0 | -92.0 | narK |
aatatcaatgATAGATAaagttatctt
|
1277862 | 1277868 | [APIORCISFBSCS], [BPP] | [13] | |
NarL-phosphorylated | repressor | nikAp1 | nd | nd | nd | nikA, nikB, nikC, nikD, nikE, nikR | nd | nd | [GEA], [BPP] | [28] | ||
NarL-phosphorylated | activator | nirBp | Sigma70 | -74.0 | -98.0 | nirB, nirD, nirC, cysG |
atcagcaataTACCCATtaaggagtat
|
3493910 | 3493916 | [GEA], [BCE], [BPP], [SM] | [12], [29], [30] | |
NarL-phosphorylated | activator | nirBp | Sigma70 | -65.0 | -89.0 | nirB, nirD, nirC, cysG |
atacccattaAGGAGTAtataaaggtg
|
3493919 | 3493925 | [GEA], [BCE], [BPP], [SM] | [12], [29], [30] | |
NarL-phosphorylated | repressor | norVp | Sigma54 | -78.0 | -115.0 | norV, norW |
tcattttgacTACTCATtaatgggcat
|
2832358 | 2832364 | [GEA], [APIORCISFBSCS] | [31] | |
NarL-phosphorylated | repressor | norVp | Sigma54 | -69.0 | -106.0 | norV, norW |
ctactcattaATGGGCAtaattttatt
|
2832367 | 2832373 | [GEA], [APIORCISFBSCS] | [31] | |
NarL-phosphorylated | activator | nrfAp | Sigma70 | -79.0 | -172.0 | nrfA, nrfB, nrfC, nrfD, nrfE, nrfF, nrfG |
agatactgacTAACTCTaaagtggtat
|
4287589 | 4287595 | [GEA], [AIBSCS], [BPP], [SM] | [12], [14], [30], [32], [33], [34] | |
NarL-phosphorylated | activator | nrfAp | Sigma70 | -70.0 | -163.0 | nrfA, nrfB, nrfC, nrfD, nrfE, nrfF, nrfG |
ctaactctaaAGTGGTAttttacatgc
|
4287598 | 4287604 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [12], [14], [30], [32], [33], [34] | |
NarL-phosphorylated | activator | nrfAp | Sigma70 | -50.0 | -143.0 | nrfA, nrfB, nrfC, nrfD, nrfE, nrfF, nrfG |
tacatgcactTACAATTgattaaagac
|
4287618 | 4287624 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [12], [14], [30], [32], [34] | |
NarL-phosphorylated | repressor | nrfAp | Sigma70 | -50.0 | -143.0 | nrfA, nrfB, nrfC, nrfD, nrfE, nrfF, nrfG |
tacatgcactTACAATTgattaaagac
|
4287618 | 4287624 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [12], [14], [30], [32], [34] | |
NarL-phosphorylated | repressor | nrfAp | Sigma70 | -22.0 | -115.0 | nrfA, nrfB, nrfC, nrfD, nrfE, nrfF, nrfG |
acattcacagTGTGGTTatttgttaca
|
4287646 | 4287652 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [12], [14], [30], [32], [34] | |
NarL-phosphorylated | activator | nuoAp2 | Sigma70 | -122.0 | -212.0 | nuoA, nuoB, nuoC, nuoE, nuoF, nuoG, nuoH, nuoI, nuoJ, nuoK, nuoL, nuoM, nuoN |
gggcattaaaTGCTAATggtgttgata
|
2405281 | 2405287 | [GEA], [APIORCISFBSCS] | ||
NarL-phosphorylated | activator | ogtp | nd | -83.0 | -131.0 | ogt |
gcgaaactggGTACTTACtattcgttag
|
1400364 | 1400371 | [GEA], [BPP], [SM] | [35], [36] | |
NarL-phosphorylated | activator | ogtp | nd | -74.0 | -122.0 | ogt |
ggtacttactATTCGTTAgtcttgccct
|
1400355 | 1400362 | [GEA], [BPP], [SM] | [35], [36] | |
NarL-phosphorylated | activator | ogtp | nd | -50.0 | -98.0 | ogt |
ccctatccacTTATCTTTttggtggtat
|
1400331 | 1400338 | [GEA], [BPP], [SM] | [35], [36] | |
NarL-phosphorylated | activator | ogtp | nd | -41.0 | -89.0 | ogt |
cttatcttttTGGTGGTAtggctgctga
|
1400322 | 1400329 | [GEA], [BPP], [SM] | [35], [36] | |
NarL-phosphorylated | repressor | ompWp | nd | -18.5 | -47.5 | ompW |
gatcatttgtTACTCCAATGTAGGTATattcgtcacg
|
1313965 | 1313981 | [GEA], [AIBSCS], [BPP] | [37] | |
NarL-phosphorylated | repressor | torCp | Sigma70 | nd | nd | torC, torA, torD | nd | nd | [IMP], [BPP] | [38] | ||
NarL-phosphorylated | repressor | ubiCp | Sigma70 | nd | nd | ubiC, ubiA | nd | nd | [GEA], [BPP] | [39] | ||
NarL-phosphorylated | activator | ydePp | Sigma70 | nd | nd | ydeP | nd | nd | [GEA], [BPP] | [40] | ||
NarL-phosphorylated | repressor | ydhYp | Sigma38 | -42.0 | -207.0 | ydhY, ydhV, ydhW, ydhX, ydhU, ydhT |
ttttaattgaTAACGATcaatgttaag
|
1754681 | 1754687 | [GEA], [APIORCISFBSCS] | [41] | |
NarL-phosphorylated | repressor | ydhYp | Sigma38 | -16.0 | -181.0 | ydhY, ydhV, ydhW, ydhX, ydhU, ydhT |
gggctcagaaTAATCACattatttttt
|
1754655 | 1754661 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [41] | |
NarL-phosphorylated | repressor | ydhYp | Sigma38 | 6.0 | -160.0 | ydhY, ydhV, ydhW, ydhX, ydhU, ydhT |
attttttctcCTAACCATaaaggattag
|
1754634 | 1754641 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [41] | |
NarL-phosphorylated | repressor | ydhYp | Sigma38 | 15.0 | -151.0 | ydhY, ydhV, ydhW, ydhX, ydhU, ydhT |
cctaaccataAAGGATTAgtttatcggc
|
1754625 | 1754632 | [GEA], [APIORCISFBSCS], [BPP], [SM] | [41] | |
NarL-phosphorylated | activator | yeaRp | Sigma70 | -48.0 | -94.0 | yeaR, yoaG |
tgctaaaaagTAACCAAtaaatggtat
|
1880039 | 1880045 | [GEA], [AIBSCS], [BPP] | [36], [42] | |
NarL-phosphorylated | activator | yeaRp | Sigma70 | -39.0 | -85.0 | yeaR, yoaG |
gtaaccaataAATGGTAtttaaaatgc
|
1880030 | 1880036 | [GEA], [AIBSCS], [BPP] | [36], [42] | |
NarL-phosphorylated | repressor | ynfEp | Sigma70 | -23.0 | -89.0 | ynfE, ynfF, ynfG, ynfH, dmsD |
taataattctTAACCCAaaatgggtag
|
1657977 | 1657983 | [AIBSCS], [BPP] | [43] | |
NarL-phosphorylated | repressor | ynfEp | Sigma70 | -14.0 | -80.0 | ynfE, ynfF, ynfG, ynfH, dmsD |
ttaacccaaaATGGGTAgactccctct
|
1657986 | 1657992 | [AIBSCS], [BPP] | [43] | |
NarL-phosphorylated | repressor | ynfEp2 | Sigma38 | -23.0 | -89.0 | ynfE, ynfF, ynfG, ynfH, dmsD |
taataattctTAACCCAaaatgggtag
|
1657977 | 1657983 | [AIBSCS], [BPP] | [43] | |
NarL-phosphorylated | repressor | ynfEp2 | Sigma38 | -14.0 | -80.0 | ynfE, ynfF, ynfG, ynfH, dmsD |
ttaacccaaaATGGGTAgactccctct
|
1657986 | 1657992 | [AIBSCS], [BPP] | [43] | |
NarL-phosphorylated | activator | ytfEp | nd | -50.0 | -76.0 | ytfE |
aataagcctcTGCTACGtaagggttat
|
4432056 | 4432062 | [AIBSCS] | [44] | |
NarL-phosphorylated | activator | ytfEp | nd | -41.0 | -67.0 | ytfE |
ctgctacgtaAGGGTTAtagcttttgc
|
4432047 | 4432053 | [AIBSCS] | [44] |
Alignment and PSSM for NarL TFBSs | ![]() |
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Aligned TFBS of NarL |
---|
Sequence | |
---|---|
ATACCCATTAAGGAGTA | |
ATACCCCGATCGGGGTA | |
ATAACCCTTACGTAGCA | |
ATACCCCTTTAGGATAA | |
CTACTCATTAATGGGCA | |
CTACCGCTATTGAGGTA | |
TTACTCACTTCTGGGTA | |
TTACCCCTTAATTATTA | |
CTAACTCTAAAGTGGTA | |
CTAATCCTTTATGGTTA | |
ATACCTACATTGGAGTA | |
ATAATGCTTTGTTAGTA | |
TTAACCCAAAATGGGTA | |
GTACCTATAAAGGAGCA | |
GTACTCACTATGGGTAA | |
ATAACGATCAATGTTAA | |
CTACCCTTACCGATGTA | |
ATACCCATACCCGGAAA | |
CTACCTATCTCTTTGAT | |
ATACCATTTATTGGTTA | |
TTACTCCTTATTTGCCG | |
TTACTCCGTATTTGCAT | |
ATACTACTTTCGAGTGA | |
GTAATTCAAAGGGAGTA | |
ATACCTCACAGTGAATA | |
CTAACGAATAGTAAGTA | |
GTAATTATAAGGTTAAA | |
TTACCGATATTTAACCT | |
TTAATGATTAGTCTGAG | |
ATACTCCTTAATACCCA | |
TTACTCCTCACTTACAC | |
ATAATCCGCCTTCGCAA | |
ATAACCACACTGTGAAT | |
TTAATTACATCCGTCAA | |
TTACCACACATTTATTA | |
CTAACCACACGGCAAAT | |
CTACCTCGATGGTTTAG | |
ATACCACCAAAAAGATA | |
ATAACTTTATCTATCAT | |
CTACCGCCAGAGAGGTA | |
ATTATGATAAGTTGGAT | |
ATAATACGTATGTTTGA | |
TAAATGCTAATGGTGTT | |
GTAACAATATCGATCGT | |
GTATTCCCCATGGGTAA | |
TTAATCAATTGTAAGTG | |
ATAATCACATTATTTTT | |
ATCCCCATCACTCTTGA | |
TTACTCATTCAATTTTT | |
TAAATAACATGTGTGAA | |
ACAATACTTTCTGGCGA | |
CAACTCATTTGTTAATT | |
CTACGCTTTATTAACAA | |
ATTACACTAATGCTTCT | |
TTATCCATCAGACTATA | |
GTTCTGTTTTGTATGAA | |
ATATCAATTTCTCATCT | |
TTACTTCGGCCGGTACA | |
ATAATTAACAGCCACCA | |
CGAATACTATGGGCAAA | |
TTACTACCAAAAATAGT | |
TTTACTTTATTTTTCAT | |
CGAACGCTATTCCACTG | |
ATTATTTTATTAATGCA | |
ATAGTGAGTACAGTGAC | |
GCACCACTGCCTGACAG | |
CTCGCGATAATCCTATT | |
CGAAATACTCCTTAGGA |
Position weight matrix (PWM). NarL matrix-quality result |
---|
A 26 3 61 30 1 13 30 7 30 33 14 7 15 22 12 24 43 C 16 2 2 33 34 27 31 13 10 9 18 5 10 2 15 11 2 G 8 3 0 2 1 13 0 7 2 1 16 24 24 20 25 7 6 T 18 60 5 3 32 15 7 41 26 25 20 32 19 24 16 26 17 |
Consensus |
---|
; consensus.strict aTAcccctaacggggta ; consensus.strict.rc TACCCCGTTAGGGGTAT ; consensus.IUPAC mTAmycmtwwskgdswa ; consensus.IUPAC.rc TWSHCMSWWAKGRKTAK ; consensus.regexp [ac]TA[ac][ct]c[ac]t[at][at][cg][gt]g[agt][cg][at]a ; consensus.regexp.rc T[AT][CG][ACT]C[AC][CG][AT][AT]A[GT]G[AG][GT]TA[GT] |
Evolutionary conservation of regulatory elements | ![]() |
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Reference(s) |
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