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YgiV DNA-binding transcriptional dual regulator

Synonyms: YgiV
YgiV had been predicted as a transcriptional regulator [2] However, based on nickel enrichment DNA microarrays and additional gel shift assays, it was identified as a transcriptional repressor of mcbR, which regulates biofilm formation and mucoidity by repressing expression of mcbA (ybiM) [1]. MqsR has a toxic effect on Escherichia coli bacterial growth, which is partially reduced by the ygiV mutation [1].

Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
YgiV Functional   [AUP], [IEP] [1]
Connectivity class: Local Regulator
Gene name: ygiV
  Genome position: 3168749-3169231
  Length: 483 bp / 160 aa
Operon name: