RegulonDB RegulonDB 9.3:Regulon Page

GlrR DNA-binding transcriptional activator

Synonyms: GlrR, GlrR-Pasp56

Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
GlrR Non-Functional   Apo [BPP], [GEA], [IDA], [IEP] [1]
GlrR-Pasp56 Functional Covalent Holo nd nd
Evolutionary Family: EBP
Connectivity class: Local Regulator
Gene name: glrR
  Genome position: 2687469-2688803
  Length: 1335 bp / 444 aa
Operon name: glrR-glnB
TU(s) encoding the TF:
Transcription unit        Promoter

Regulated gene(s) glmY
Multifun term(s) of regulated gene(s)
posttranscriptional (1)
Regulated operon(s) glmY
First gene in the operon(s) glmY
Simple and complex regulons GlrR,IHF
Simple and complex regulatory phrases Regulatory phrase (List of promoters regulated by the phrase)

Transcription factor binding sites (TFBSs) arrangements       

  Functional conformation Function Promoter Sigma factor Central Rel-Pos Distance to first Gene Genes Sequence LeftPos RightPos Evidence (Confirmed, Strong, Weak) References
  GlrR-Pasp56 activator glmYp1 Sigma54 -221.5 -221.5 glmY
2691553 2691570 [BPP], [GEA], [HIBSCS], [SM] [1]
  GlrR-Pasp56 activator glmYp1 Sigma54 -188.5 -188.5 glmY
2691520 2691537 [BPP], [GEA], [HIBSCS], [SM] [1]
  GlrR-Pasp56 activator glmYp1 Sigma54 -125.5 -125.5 glmY
2691457 2691474 [BPP], [GEA], [HIBSCS], [SM] [1]

Evolutionary conservation of regulatory elements    
     Note: Evolutionary conservation of regulatory interactions and promoters is limited to gammaproteobacteria.
Promoter-target gene evolutionary conservation


 [BPP] Binding of purified proteins

 [GEA] Gene expression analysis

 [IDA] Inferred from direct assay

 [IEP] Inferred from expression pattern

 [HIBSCS] Human inference based on similarity to consensus sequences

 [SM] Site mutation


 [1] Reichenbach B., Gopel Y., Gorke B., 2009, Dual control by perfectly overlapping sigma(54)- and sigma(70)-promoters adjusts small RNA GlmY expression to different environmental signals., Mol Microbiol. 74(5):1054-70