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AidB DNA-binding transcriptional repressor

Synonyms: AidB


Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
AidB     nd nd
Evolutionary Family: AidB_like
Connectivity class: Local Regulator
Gene name: aidB
  Genome position: 4414275-4415900
  Length: 1626 bp / 541 aa
Operon name: aidB
TU(s) encoding the TF:
Transcription unit        Promoter
aidB
aidBp


Regulon       
Regulated gene(s) aidB
Multifun term(s) of regulated gene(s)
repressor (1)
Regulated operon(s) aidB
First gene in the operon(s) aidB
Simple and complex regulons Ada,AidB,Lrp
Simple and complex regulatory phrases Regulatory phrase (List of promoters regulated by the phrase)


Transcription factor binding sites (TFBSs) arrangements       

  Functional conformation Function Promoter Sigma factor Central Rel-Pos Distance to first Gene Genes Sequence LeftPos RightPos Evidence (Confirmed, Strong, Weak) References
  AidB repressor aidBp Sigma70 -48.0 -76.5 aidB
ttacattgctGGATAAGAATGTTTTAGCAATCTCTTtctgtcatga
4414186 4414211 [BPP], [GEA] [1]


Evolutionary conservation of regulatory elements    
     Note: Evolutionary conservation of regulatory interactions and promoters is limited to gammaproteobacteria.
Promoter-target gene evolutionary conservation


Evidence    

 [BPP] Binding of purified proteins

 [GEA] Gene expression analysis



Reference(s)    

 [1] Rippa V., Amoresano A., Esposito C., Landini P., Volkert M., Duilio A., 2010, Specific DNA binding and regulation of its own expression by the AidB protein in Escherichia coli., J Bacteriol. 192(23):6136-42



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