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AidB DNA-binding transcriptional repressor

Synonyms: AidB


Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
AidB     nd nd
Evolutionary Family: AidB_like
Connectivity class: Local Regulator
Gene name: aidB
  Genome position: 4414275-4415900
  Length: 1626 bp / 541 aa
Operon name: aidB
TU(s) encoding the TF:
Transcription unit        Promoter
aidB
aidBp


Regulon       
Regulated gene(s) aidB
Multifun term(s) of regulated gene(s)
repressor (1)
Regulated operon(s) aidB
First gene in the operon(s) aidB
Simple and complex regulons Ada,Lrp,isovaleryl-CoA
Simple and complex regulatory phrases Regulatory phrase (List of promoters regulated by the phrase)


Transcription factor binding sites (TFBSs) arrangements       

  Functional conformation Function Promoter Sigma factor Central Rel-Pos Distance to first Gene Genes Sequence LeftPos RightPos Evidence (Confirmed, Strong, Weak) References
  AidB repressor aidBp Sigma70 -48.0 -76.5 aidB
ttacattgctGGATAAGAATGTTTTAGCAATCTCTTtctgtcatga
4414186 4414211 [BPP], [GEA] [1]


Evolutionary conservation of regulatory elements    
     Note: Evolutionary conservation of regulatory interactions and promoters is limited to gammaproteobacteria.
Promoter-target gene evolutionary conservation


Evidence    

 [BPP] Binding of purified proteins

 [GEA] Gene expression analysis



Reference(s)    

 [1] Rippa V., Amoresano A., Esposito C., Landini P., Volkert M., Duilio A., 2010, Specific DNA binding and regulation of its own expression by the AidB protein in Escherichia coli., J Bacteriol. 192(23):6136-42



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