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DecR DNA-binding transcriptional dual regulator

Synonyms: DecR
DecR is a regulator with an important role in cysteine detoxification. The absence of decR increases the inhibitory effect on bacterial growth caused by cysteine [4]. The presence of cysteine improves the interaction between DecR and the promoter region of the operon yhaOM, thereby causing activation [4]. DecR (YbaO) may have a role in Rob-mediated regulation [1]. In a Salmonella enterica cutR mutant, E. coli ybaO restored cysteine-responsive regulation of the CdsH cysteine desulfhydrase []. decR is a member of the Rob regulon [1]. Based on transcript profiling with a cutR mutant and overpression of cutR under anaerobic cysteine growth conditions, 37 genes showed at least a 5-fold change in expression, with increased expression of 20 genes and diminished expression of 17 genes [5].
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Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
DecR Functional   [APPPINH],