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OmpR DNA-binding transcriptional dual regulator

Synonyms: OmpR-phosphorylated, OmpR


Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) References
OmpR Functional   Apo nd nd nd
OmpR-phosphorylated Functional Covalent Holo nd nd nd
TFBs length: 20
TFBs symmetry: direct-repeat
Sensing class: External-Two-component systems
Connectivity class: Local Regulator
Gene name: ompR
  Genome position: 3535865-3536584
  Length: 720 bp / 239 aa
Operon name: ompR-envZ
TU(s) encoding the TF:
Transcription unit        Promoter
ompR-envZ
ompRp1
ompR-envZ
ompRp2
ompR-envZ
ompRp3
ompR-envZ
ompRp4


Regulon       
Regulated gene(s) bolA, cadA, cadB, cadC, csgD, csgE, csgF, csgG, dtpA, ecnB, fadL, feoA, feoB, feoC, flhC, flhD, micF, nmpC, ompC, ompF, omrA, omrB, pgaA, pgaB, pgaC, pgaD, sra
Multifun term(s) of regulated gene(s) MultiFun Term (List of genes associated to the multifun term)
Transcription related (5)
activator (5)
repressor (4)
membrane (4)
Beta barrel porins (The Outer Membrane Porin (OMP) Functional Superfamily) (4)
Read more >
Regulated operon(s) bdm-sra, bolA, cadBA, cadC, csgDEFG, dtpA, ecnAB, fadL, feoABC, flhDC, micF, nmpC, ompC, ompF, omrA, omrB, pgaABCD
First gene in the operon(s) bolA, cadB, cadC, csgD, ecnB, fadL, feoA, flhD, micF, ompC, ompF, omrA, omrB, pgaA, sra, dtpA
Simple and complex regulons AcrR,CRP,FliZ,Fur,H-NS,HdfR,IHF,LrhA,MatA,OmpR,QseB,RcsAB,YjjQ
AcrR,H-NS,HU,IHF,Lrp,MarA,OmpR,Rob,SoxS
ArcA,CRP,FadR,OmpR,PhoP,Rob,ppGpp
ArcA,CadC,GadE-RcsB,GadX,H-NS,Lrp,OmpR
BasR,BolA,BtsR,CRP,CpxR,Cra,CsgD,FliZ,H-NS,IHF,MlrA,MqsA,OmpR,RcdA,RcsAB,RstA,ppGpp
Read more >
Simple and complex regulatory phrases Regulatory phrase (List of promoters regulated by the phrase)
[OmpR,-](12)
[OmpR,+](11)


Transcription factor regulation    


Transcription factor binding sites (TFBSs) arrangements
      

  Functional conformation Function Promoter Sigma factor Central Rel-Pos Distance to first Gene Genes Sequence
LeftPos RightPos Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) References
  OmpR-phosphorylated repressor bolAp Sigma38 -47.5 -85.5 bolA
aggacgaaacCTAAATATTTGTTGTTAAGCtgcaatggaa
454377 454396 [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] nd [1]
  OmpR-phosphorylated repressor bolAp1 Sigma70 -47.5 -85.5 bolA
aggacgaaacCTAAATATTTGTTGTTAAGCtgcaatggaa
454377 454396 [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] nd [1]
  OmpR repressor cadBp Sigma70 nd nd cadB, cadA nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [2]
  OmpR repressor cadCp Sigma70 nd nd cadC nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [2]
  OmpR-phosphorylated activator csgDp1 Sigma70 -49.5 -197.5 csgD, csgE, csgF, csgG
aatataacgaGTTACATTTAGTTACATGTTtaacacttga
1103384 1103403 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [3], [4], [5]
  OmpR-phosphorylated activator csgDp3 Sigma38 -49.5 -197.5 csgD, csgE, csgF, csgG
aatataacgaGTTACATTTAGTTACATGTTtaacacttga
1103384 1103403 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [3], [4], [5]
  OmpR-phosphorylated repressor ecnBp Sigma38 18.5 -26.5 ecnB
tttgctatagGCAAACATAAATAACATTACctaaaaggaa
4376517 4376536 [COMP-HINF-SIMILAR-TO-CONSENSUS] nd [6]
  OmpR-phosphorylated repressor fadLp Sigma38 -149.5 -250.5 fadL
gataagtgacCGAAATCACACTTAAAAATGatctaaaaca
2461046 2461065 [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IMP-SITE-MUTATION] nd
  OmpR-phosphorylated repressor fadLp Sigma38 -60.5 -161.5 fadL
atcgcgtttcTTAGATCATATTTGAAAAAAgatagaaaca
2461135 2461154 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] W [7]
  OmpR-phosphorylated repressor fadLp Sigma38 69.5 -32.5 fadL
gttacagcacGTAACATAGTTTGTATAAAAataaatcatt
2461264 2461283 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] W [7]
  OmpR-phosphorylated repressor fadLp Sigma38 119.5 18.5 fadL
tcatgagccaGAAAACCCTGTTTACAAAGTctgctctcgc
2461314 2461333 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] W [7]
  OmpR-phosphorylated activator feoAp Sigma70 -178.0 -284.0 feoA, feoB, feoC
ccggcaatatTTATCATTTCATTAACAACTgaaaccttaa
3539869 3539888 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [8]
  OmpR-phosphorylated repressor flhDp Sigma70 -145.5 -343.5 flhD, flhC
caaagtcatcGGGCATTATCTGAACATAAAacactatcaa
1978531 1978550 [COMP-HINF-SIMILAR-TO-CONSENSUS] nd
  OmpR-phosphorylated repressor flhDp Sigma70 18.5 -180.5 flhD, flhC
tcgatttaggAAAAATCTTAGATAAGTGTAaagacccatt
1978368 1978387 [COMP-HINF-SIMILAR-TO-CONSENSUS] nd
  OmpR-phosphorylated activator micFp1 Sigma70 -206.5 -206.5 micF
atccaacacgAATATGATACTAAAACTTTTaagatgtttc
2312868 2312887 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [9], [10], [11], [12], [13]
  OmpR-phosphorylated activator micFp1 Sigma70 -186.5 -186.5 micF
taaaacttttAAGATGTTTCATTTATCGCTatagatgttt
2312888 2312907 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [9], [10], [11], [13], [14]
  OmpR-phosphorylated activator micFp1 Sigma70 -165.5 -165.5 micF
tttatcgctaTAGATGTTTCAAAATGTAAAtgcaagggaa
2312909 2312928 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [8], [9], [10], [11], [13], [14]
  OmpR-phosphorylated activator micFp2 Sigma38 -206.5 -206.5 micF
atccaacacgAATATGATACTAAAACTTTTaagatgtttc
2312868 2312887 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [9], [10], [11], [12], [13]
  OmpR-phosphorylated activator micFp2 Sigma38 -186.5 -186.5 micF
taaaacttttAAGATGTTTCATTTATCGCTatagatgttt
2312888 2312907 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [9], [10], [11], [13], [14]
  OmpR-phosphorylated activator micFp2 Sigma38 -165.5 -165.5 micF
tttatcgctaTAGATGTTTCAAAATGTAAAtgcaagggaa
2312909 2312928 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [8], [9], [10], [11], [13], [14]
  OmpR-phosphorylated repressor nmpCp nd -45.5 nd nmpC
aatcaaacgaGAAACCAAAACTTACATCTTgaaataatca
576906 576925 [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IMP-SITE-MUTATION] nd [15]
  OmpR-phosphorylated activator ompCp1 Sigma70 -88.5 -169.5 ompC
ttcccttgcaTTTACATTTTGAAACATCTAtagcgataaa
2312909 2312928 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [8], [9], [10], [11], [13], [14], [16]
  OmpR-phosphorylated activator ompCp1 Sigma70 -67.5 -148.5 ompC
aaacatctatAGCGATAAATGAAACATCTTaaaagtttta
2312888 2312907 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [9], [10], [11], [13], [14], [16]
  OmpR-phosphorylated activator ompCp1 Sigma70 -47.5 -128.5 ompC
gaaacatcttAAAAGTTTTAGTATCATATTcgtgttggat
2312868 2312887 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [9], [10], [11], [12], [13], [16]
  OmpR-phosphorylated repressor ompFp Sigma70 -370.5 -480.5 ompF
cgatcatcctGTTACGGAATATTACATTGCaacatttacg
987453 987472 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [13], [16], [17], [18], [19]
  OmpR-phosphorylated activator ompFp Sigma70 -90.5 -200.5 ompF
ttccttaaatTTTACTTTTGGTTACATATTttttcttttt
987173 987192 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [20], [21], [22], [23]
  OmpR-phosphorylated activator ompFp Sigma70 -70.5 -180.5 ompF
gttacatattTTTTCTTTTTGAAACCAAATctttatcttt
987153 987172 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [16], [20], [21], [22], [23], [24], [25]
  OmpR-phosphorylated repressor ompFp Sigma70 -70.5 -180.5 ompF
gttacatattTTTTCTTTTTGAAACCAAATctttatcttt
987153 987172 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [16], [20], [21], [22], [23], [24], [25]
  OmpR-phosphorylated activator ompFp Sigma70 -50.5 -160.5 ompF
gaaaccaaatCTTTATCTTTGTAGCACTTTcacggtagcg
987133 987152 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [17], [18], [19], [20], [21], [22], [23], [24]
  OmpR-phosphorylated repressor ompFp Sigma70 -50.5 -160.5 ompF
gaaaccaaatCTTTATCTTTGTAGCACTTTcacggtagcg
987133 987152 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [17], [18], [19], [20], [21], [22], [23], [24]
  OmpR-phosphorylated repressor ompFp2 Sigma38 -370.5 -480.5 ompF
cgatcatcctGTTACGGAATATTACATTGCaacatttacg
987453 987472 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [13], [16], [17], [18], [19]
  OmpR-phosphorylated activator ompFp2 Sigma38 -90.5 -200.5 ompF
ttccttaaatTTTACTTTTGGTTACATATTttttcttttt
987173 987192 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [20], [21], [22], [23]
  OmpR-phosphorylated activator ompFp2 Sigma38 -70.5 -180.5 ompF
gttacatattTTTTCTTTTTGAAACCAAATctttatcttt
987153 987172 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [16], [20], [21], [22], [23], [24], [25]
  OmpR-phosphorylated repressor ompFp2 Sigma38 -70.5 -180.5 ompF
gttacatattTTTTCTTTTTGAAACCAAATctttatcttt
987153 987172 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [16], [20], [21], [22], [23], [24], [25]
  OmpR-phosphorylated activator ompFp2 Sigma38 -50.5 -160.5 ompF
gaaaccaaatCTTTATCTTTGTAGCACTTTcacggtagcg
987133 987152 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [17], [18], [19], [20], [21], [22], [23], [24]
  OmpR-phosphorylated repressor ompFp2 Sigma38 -50.5 -160.5 ompF
gaaaccaaatCTTTATCTTTGTAGCACTTTcacggtagcg
987133 987152 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] C [10], [12], [13], [14], [17], [18], [19], [20], [21], [22], [23], [24]
  OmpR-phosphorylated activator omrAp nd -70.5 -70.5 omrA
accgacaattTACACACCTCGTTGCATTTCccttcattcc
2976250 2976269 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] W [26]
  OmpR-phosphorylated activator omrBp nd -71.5 -71.5 omrB
aaagagattgCAAACCTTTGGTTACACTTTgcgaaacgct
2976447 2976466 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] W [26]
  OmpR-phosphorylated repressor pgaAp nd -31.5 -265.5 pgaA, pgaB, pgaC, pgaD
tgcatcggaaTTTACTGATTTAATTATTTTaatcctaatt
1092545 1092564 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [27]
  OmpR-phosphorylated repressor srap Sigma38 nd nd sra nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS] W [28]
  OmpR-phosphorylated activator tppBp Sigma70 -45.5 -143.5 dtpA
tcagttatatGTAACAGATTATTACAAAGGacttgtctga
1712616 1712635 [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [29]



High-throughput Transcription factor binding sites (TFBSs)
      

  Functional conformation Function Object name Object type Distance to first Gene Sequence LeftPos RightPos Center Position Growth Condition Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) References
  OmpR repressor speF-potE Transcription-Unit nd
nd
nd nd nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [2]
  OmpR-phosphorylated activator sstT Gene nd
aaacactttgTTACATCCTGAAAGATGCGTCgacagaacgc
3239875 3239895 3239884.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator rob Gene nd
gtaatagataAAAATGGTAACAATATGAAATacaagcattt
4635507 4635527 4635516.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator fadE Gene nd
gtggatgtaaAAACATTTAGCAATATGTTTAcaatataatt
243369 243389 243378.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator acrR Gene nd
acatacattcACAAATGTATGTAAATCTAACgcctgtaaat
485720 485740 485729.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator rhtA Gene nd
gagtttcccaTTAATTTTTGATATATTTAAAacttaggact
850394 850414 850403.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator pdhR Gene nd
ctttgaaacgTTATATATGTCAAGTTGTTAAaatgtgcaca
121941 121961 121950.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator ompX Gene nd
gagtttcccaTTAATTTTTGATATATTTAAAacttaggact
850394 850414 850403.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator gmhA Gene nd
gtggatgtaaAAACATTTAGCAATATGTTTAcaatataatt
243369 243389 243378.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator tolC Gene nd
taatttctacATCGTTTTTGCCAAATGTAACgggcaggttg
3177866 3177886 3177875.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator tsgA Gene nd
tacctaatttTACGTATCTGAAATATATGTAacctgacgat
3492387 3492407 3492396.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated activator narU Gene nd
aagtagccagATATGTGTTACTAAATGTAACtaacaagcta
1544223 1544243 1544232.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
  OmpR-phosphorylated repressor lpp Gene nd
tcaacataaaAAACTTTGTGTAATACTTGTAacgctacatg
1757360 1757380 1757369.5 nd [EXP-IEP-MICROARRAY], [COMP-AINF-PATTERN-DISCOVERY], [EXP-GSELEX] S [30]
Other High-throughput regulatory interactions with weak evidence


Alignment and PSSM for OmpR TFBSs    

Aligned TFBS of OmpR   
  Sequence
  AATATGTAACCAAAAGTAAAAT
  AACATGTAACTAAATGTAACTC
  AACGAGAAACCAAAACTTACAT
  AAAGTGTAACCAAAGGTTTGCA
  AATATGATACTAAAACTTTTAA
  TATATGTAACAGATTATTACAA
  TAGATGTTTCAAAATGTAAATG
  ATCCTGTTACGGAATATTACAT
  GAAATGCAACGAGGTGTGTAAA
  AAAGTGCTACAAAGATAAAGAT
  TATAGGCAAACATAAATAACAT
  ATTTGGTTTCAAAAAGAAAAAA
  AGCACGTAACATAGTTTGTATA
  TACACTTATCTAAGATTTTTCC
  TATCTTTTTTCAAATATGATCT
  TGACCGAAATCACACTTAAAAA
  GCAGCTTAACAACAAATATTTA
  TTAAAATAATTAAATCAGTAAA
  ACTTTGTAAACAGGGTTTTCTG
  GGGCATTATCTGAACATAAAAC
  TCTATAGCGATAAATGAAACAT

Position weight matrix (PWM). OmpR matrix-quality result   
A	10	12	6	11	3	2	3	14	15	3	6	17	16	15	8	6	4	10	13	8	13	9
C	0	3	5	4	4	0	3	1	0	15	7	0	2	0	2	3	0	0	0	7	3	3
G	3	3	2	4	2	15	1	0	1	0	2	3	2	5	2	7	0	4	0	2	0	2
T	8	3	8	2	12	4	14	6	5	3	6	1	1	1	9	5	17	7	8	4	5	7

Consensus   
;	consensus.strict             	aatatGtaaCcaaatgtaacaa
;	consensus.strict.rc          	TTGTTACATTTGGTTACATATT
;	consensus.IUPAC              	wayatGtaaCcaarwgtwwmaw
;	consensus.IUPAC.rc           	WTKWWACWYTTGGTTACATRTW
;	consensus.regexp             	[at]a[ct]atGtaaCcaa[ag][at]gt[at][at][ac]a[at]
;	consensus.regexp.rc          	[AT]T[GT][AT][AT]AC[AT][CT]TTGGTTACAT[AG]T[AT]

PWM logo   


 


Evolutionary conservation of regulatory elements    
     Note: Evolutionary conservation of regulatory interactions and promoters is limited to gammaproteobacteria.
TF-target gene evolutionary conservation
Promoter-target gene evolutionary conservation




Reference(s)    

 [1] Yamamoto K., Nagura R., Tanabe H., Fujita N., Ishihama A., Utsumi R., 2000, Negative regulation of the bolA1p of Escherichia coli K-12 by the transcription factor OmpR for osmolarity response genes., FEMS Microbiol Lett 186(2):257-62

 [2] Chakraborty S., Winardhi RS., Morgan LK., Yan J., Kenney LJ., 2017, Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells., Nat Commun 8(1):1587

 [3] Jubelin G., Vianney A., Beloin C., Ghigo JM., Lazzaroni JC., Lejeune P., Dorel C., 2005, CpxR/OmpR interplay regulates curli gene expression in response to osmolarity in Escherichia coli., J Bacteriol 187(6):2038-49

 [4] Ogasawara H., Yamada K., Kori A., Yamamoto K., Ishihama A., 2010, Regulation of the Escherichia coli csgD promoter: interplay between five transcription factors., Microbiology 156(Pt 8):2470-83

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