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XynR DNA-binding transcriptional dual regulator

Synonyms: XynR-D-xylonate
Summary:
Based on SELEX screening of Escherichia coli K-12 W3110, XynR, formerly known as YgadI, was identified as a regulator of xylonate catabolism; it is a rare single-target TF, and its regulation network is still fixed within the CR4-6 prophage without significant cross-talk with the host. It regulates the bidirectional transcripts yagA(b) and yagEF(GH) [1] A single peak of XynR binding was identified within the spacer of bidirectional transcription units of the yagA and yagEF operons. However, by decreasing the cutoff of detection, approximately 30 low-level peaks were detected, which are all located inside open reading frames (ORFs) [1] The level of XynR was detectable in the exponential growth phase, but it decreased to an undetectable level during growth in the stationary phase [1] XynR: xylonate catabolism regulator [1] A yagI mutant shows increased biofilm formation compared to wild type, but a lower increase in biofilm formation when the derepressed conjugative plasmid R1drd19 is present [2]. Read more >


Transcription factor      
TF conformation(s):
Name Conformation Type TF-Effector Interaction Type Apo/Holo Conformation Evidence (Confirmed, Strong, Weak) References
XynR-D-xylonate Functional   nd nd
Evolutionary Family: IclR
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