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FliZ,RutR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
RutR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional dual regulator RutR, YcdC
Gene name(s): rutR
Functional conformation(s): RutR-uracil , RutR-thymine , RutR
Coregulator(s): ArcA, FNR, Fis, FliZ, Fur, GadE, GadW, GadX, H-NS, IHF, NemR, NtrC, PepA, PhoB, PhoP, PurR, RutR
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
FliZ      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional regulator FliZ, YedH
Gene name(s): fliZ
Functional conformation(s): FliZ
Coregulator(s): AcrR, AdiY, BasR, CRP, CpxR, Cra, CsgD, EvgA, Fis, FliZ, Fur, GadE, GadW, GadX, H-NS, HdfR, IHF, LrhA, Lrp, MarA, MatA, MlrA, MqsA, OmpR, PhoP, QseB, RcdA, RcsB, RstA, RutR, TorR, YdeO, YjjQ, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY FliZ,RutR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
FliZ repressor RutR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
RutR repressor pdeRp pdeR         [GEA] [1]
FliZ repressor pdeRp pdeR 1346857 1346905 -37.5 atccaggcagATTTTTTAACTGACTTTCGTTTGAAAACTGGCGTTTTTCCAAAACTGGAttacaaataa [BPP]
[GEA]
[SM]
[2]
[3]

Evidence: [GEA] Gene expression analysis
[BPP] Binding of purified proteins
[SM] Site mutation
Reference(s): [1] Shimada T., et al., 2007
[2] Pesavento C., et al., 2008
[3] Pesavento C., et al., 2012



Reference(s)    

 [1] Shimada T., Hirao K., Kori A., Yamamoto K., Ishihama A., 2007, RutR is the uracil/thymine-sensing master regulator of a set of genes for synthesis and degradation of pyrimidines., Mol Microbiol 66(3):744-57

 [2] Pesavento C., Becker G., Sommerfeldt N., Possling A., Tschowri N., Mehlis A., Hengge R., 2008, Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli., Genes Dev 22(17):2434-46

 [3] Pesavento C., Hengge R., 2012, The global repressor FliZ antagonizes gene expression by σS-containing RNA polymerase due to overlapping DNA binding specificity., Nucleic Acids Res 40(11):4783-93


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