RegulonDB RegulonDB 10.6.3: Regulon Form
   
   


ZntR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
ZntR      Tractordb tool
Connectivity class Local Regulator
Sensing Class External sensing using transported metabolites
Synonym(s): ZntR-Zn2+ DNA-binding transcriptional activator
Gene name(s): zntR
Functional conformation(s): ZntR-Cd2+ , ZntR-Hg , ZntR , ZntR-Zn2+
Coregulator(s): ZntR
Summary: TF Summary ...[more]

REGULATION EXERTED BY ZntR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
ZntR activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
ZntR-Zn2+ activator zntAp zntA 3606387 3606408 -24.5 ataaaacttgACTCTGGAGTCGACTCCAGAGTgtatccttcg [BPP]
[SM]
[1]
[2]

Evidence: [BPP] Binding of purified proteins
[SM] Site mutation
Reference(s): [1] Brocklehurst KR., et al., 1999
[2] Outten CE., et al., 1999



Reference(s)    

 [1] Brocklehurst KR., Hobman JL., Lawley B., Blank L., Marshall SJ., Brown NL., Morby AP., 1999, ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA in Escherichia coli., Mol Microbiol 31(3):893-902

 [2] Outten CE., Outten FW., O'Halloran TV., 1999, DNA distortion mechanism for transcriptional activation by ZntR, a Zn(II)-responsive MerR homologue in Escherichia coli., J Biol Chem 274(53):37517-24


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