RegulonDB RegulonDB 10.6.3: Regulon Form
   
   


BasR,Fis regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
Fis Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class TFs for DNA-bending
Synonym(s): DNA-binding transcriptional dual regulator Fis, Nbp, site-specific DNA inversion stimulation factor
Gene name(s): fis
Functional conformation(s): Fis
Coregulator(s): AcrR, AdiY, AppY, ArcA, ArgP, BasR, CRP, CpxR, Cra, CreB, CspA, CusR, CytR, DeoR, DksA, DksA-ppGpp, DnaA, FNR, FadR, Fis, FlhDC, FliZ, Fur, GadE, GadW, GadX, GlcC, GlpR, H-NS, HprR, IHF, IscR, LeuO, Lrp, MalT, MarA, MarR, MazE, Mlc, MntR, ModE, NanR, NarL, NarP, NrdR, NsrR, NtrC, OmpR, OxyR, PdhR, PepA, PurR, RcsB, Rob, RstA, RutR, SlyA, SoxS, StpA, TorR, XylR, YdeO, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
BasR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): BasR response regulator, DNA-binding transcriptional dual regulator BasR, PmrA
Gene name(s): basR
Functional conformation(s): BasR-Phosphorylated
Coregulator(s): BasR, CRP, CpxR, Cra, CsgD, DksA, DksA-ppGpp, Fis, FliZ, H-NS, IHF, MarA, MlrA, MqsA, NagC, NanR, OmpR, PdhR, PhoP, PutA, QseB, RcdA, RcsB, RstA, SoxR, SoxS, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY BasR,Fis Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
BasR activator Fis repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
Fis repressor cspIp cspI 1638893 1638907 -88.0 agaatgacacGTTTTATTAATAAATaaagctattc [AIBSCS]
[GEA]
[1]
Fis repressor cspIp cspI 1638888 1638902 -83.0 gacacgttttATTAATAAATAAAGCtattctttca [AIBSCS]
[GEA]
[1]
Fis repressor cspIp cspI 1638825 1638839 -20.0 ccttgctatgGGTGGTTAATCATGCgttaatggtg [AIBSCS]
[GEA]
[1]
Fis repressor cspIp cspI 1638792 1638806 14.0 tgttctggttTGTTACAAATTTATCtgaagcagtc [AIBSCS]
[GEA]
[1]
Fis repressor cspIp cspI 1638765 1638779 41.0 aagcagtcatTGTTATAATTTTATTatttgtacct [AIBSCS]
[GEA]
[1]
Fis repressor cspIp cspI 1638757 1638771 49.0 attgttataaTTTTATTATTTGTACctcttgagat [AIBSCS]
[GEA]
[1]
BasR-Phosphorylated activator cspIp cspI 1638940 1638959 -137.5 tccatgagccAAAATTCCTGAAATCTTAAGggtaagataa [BPP]
[HIBSCS]
[2]

Evidence: [AIBSCS] Automated inference based on similarity to consensus sequences
[GEA] Gene expression analysis
[BPP] Binding of purified proteins
[HIBSCS] Human inference based on similarity to consensus sequences
Reference(s): [1] Bradley MD., et al., 2007
[2] Ogasawara H., et al., 2012



Reference(s)    

 [1] Bradley MD., Beach MB., de Koning AP., Pratt TS., Osuna R., 2007, Effects of Fis on Escherichia coli gene expression during different growth stages., Microbiology 153(Pt 9):2922-40

 [2] Ogasawara H., Shinohara S., Yamamoto K., Ishihama A., 2012, Novel regulation targets of the metal-response BasS-BasR two-component system of Escherichia coli., Microbiology 158(Pt 6):1482-92


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