RegulonDB RegulonDB 10.6.3: Regulon Form
   
   


DeoR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
DeoR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional repressor DeoR, NucR, transcriptional repressor for deo operon, tsx, nupG
Gene name(s): deoR
Functional conformation(s): DeoR-Deoxyribose-5-phosphate , DeoR
Coregulator(s): CRP, CytR, DeoR, Fis, ModE
Summary: TF Summary ...[more]

REGULATION EXERTED BY DeoR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
DeoR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
DeoR repressor deoCp1 deoC , deoA , deoB , deoD 4616663 4616678 -8.0 atctcgtcttGTGTTAGAATTCTAACatacggttgc [HIBSCS]
[SM]
[1]
[2]
DeoR repressor deoCp1 deoC , deoA , deoB , deoD 4616939 4616954 269.0 gcaggaagctGTGGGTAAGGCAGATTgttttctgct [HIBSCS]
[SM]
[1]
[2]
DeoR repressor deoCp1 deoC , deoA , deoB , deoD 4616063 4616078 -608.0 cgcgcggcaaTCCCTTCTTTTTCACAcagcaagtta [HIBSCS]
[SM]
[1]
[2]
DeoR repressor tsxp1 tsx 432245 432260 -7.5 cccgtcatttTGTTACTCTGCTTACAtcacctggat [BCE]
[GEA]
[3]
[4]

Evidence: [HIBSCS] Human inference based on similarity to consensus sequences
[SM] Site mutation
[BCE] Binding of cellular extracts
[GEA] Gene expression analysis
Reference(s): [1] Amouyal M., et al., 1989
[2] Valentin-Hansen P., et al., 1986
[3] Bremer E., et al., 1988
[4] Bremer E., et al., 1990



Reference(s)    

 [1] Amouyal M., Mortensen L., Buc H., Hammer K., 1989, Single and double loop formation when deoR repressor binds to its natural operator sites., Cell 58(3):545-51

 [2] Valentin-Hansen P., Albrechtsen B., Love Larsen JE., 1986, DNA-protein recognition: demonstration of three genetically separated operator elements that are required for repression of the Escherichia coli deoCABD promoters by the DeoR repressor., EMBO J 5(8):2015-21

 [3] Bremer E., Gerlach P., Middendorf A., 1988, Double negative and positive control of tsx expression in Escherichia coli., J Bacteriol 170(1):108-16

 [4] Bremer E., Middendorf A., Martinussen J., Valentin-Hansen P., 1990, Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli., Gene 96(1):59-65


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