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PgrR,TyrR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
TyrR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Sensing external and internal signals
Synonym(s): DNA-binding transcriptional dual regulator TyrR
Gene name(s): tyrR
Functional conformation(s): TyrR-tyrosine , TyrR-L-tryptophan , TyrR , TyrR-phenylalanine
Coregulator(s): CpxR, Cra, HU, IHF, PgrR, SoxR, TrpR, TyrR
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
PgrR      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional repressor PgrR, YcjZ
Gene name(s): pgrR
Functional conformation(s): PgrR
Coregulator(s): PgrR, TyrR
Summary: TF Summary ...[more]

REGULATION EXERTED BY PgrR,TyrR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
PgrR repressor TyrR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
TyrR repressor tyrRp tyrR 1386588 1386605 -95.5 tatcgggtgcTGACCGGATATCTTTACGccgaagtgcc [GEA]
[HIBSCS]
[1]
[2]
TyrR repressor tyrRp tyrR 1386632 1386649 -51.5 tccgtctttgTGTCAATGATTGTTGACAgaaaccttcc [GEA]
[HIBSCS]
[1]
[3]
PgrR repressor tyrRp tyrR         [BPP]
[GEA]
[IGI]
[4]

Evidence: [GEA] Gene expression analysis
[HIBSCS] Human inference based on similarity to consensus sequences
[BPP] Binding of purified proteins
[IGI] Inferred from genetic interaction
Reference(s): [1] Camakaris H., et al., 1982
[2] Pittard AJ., et al., 1991
[3] Cornish EC., et al., 1986
[4] Choi U., et al., 2016



Reference(s)    

 [1] Camakaris H., Pittard J., 1982, Autoregulation of the tyrR gene., J Bacteriol 150(1):70-5

 [2] Pittard AJ., Davidson BE., 1991, TyrR protein of Escherichia coli and its role as repressor and activator., Mol Microbiol 5(7):1585-92

 [3] Cornish EC., Argyropoulos VP., Pittard J., Davidson BE., 1986, Structure of the Escherichia coli K12 regulatory gene tyrR. Nucleotide sequence and sites of initiation of transcription and translation., J Biol Chem 261(1):403-10

 [4] Choi U., Park YH., Kim YR., Seok YJ., Lee CR., 2016, Increased expression of genes involved in uptake and degradation of murein tripeptide under nitrogen starvation in Escherichia coli., FEMS Microbiol Lett 363(14)


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