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CRP,GlpR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
CRP Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class Using internal synthesized signals
Synonym(s): Cap, Csm, DNA-binding transcriptional dual regulator CRP, GurB
Gene name(s): crp
Functional conformation(s): CRP-cAMP , CRP
Coregulator(s): AcrR, AdiY, AgaR, AraC, ArcA, ArgP, ArgR, AscG, BasR, BtsR, CRP, CaiF, ChbR, ComR, CpxR, Cra, CreB, CsgD, CspA, CsqR, CusR, CytR, DcuR, DeoR, DgoR, DksA-ppGpp, DnaA, DpiA, DsdC, EbgR, EnvY, EvgA, ExuR, FNR, FadR, FeaR, FhlA, Fis, FlhDC, FliZ, FucR, Fur, GadE, GadW, GadX, GalR, GalS, GatR, GcvA, GlaR, GlcC, GlpR, GlrR, GntR, GutM, H-NS, HU, HdfR, HipB, HprR, HyfR, HypT, IHF, IclR, IdnR, LacI, LeuO, LexA, LrhA, Lrp, LsrR, MalI, MalT, MarA, MarR, MatA, McbR, MelR, MetJ, MhpR, Mlc, MlrA, ModE, MprA, MqsA, MurR, Nac, NadR, NagC, NanR, NarL, NarP, NrdR, NsrR, NtrC, OmpR, OxyR, PaaX, PdhR, PhoB, PhoP, PrpR, PurR, PuuR, QseB, RbsR, RcdA, RcsB, RhaR, RhaS, Rob, RstA, SdiA, SlyA, SoxR, SoxS, SrlR, StpA, TdcA, TdcR, TorR, TreR, UhpA, UidR, UlaR, UvrY, UxuR, XylR, YdeO, YiaJ, YjjQ, ZraR, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
GlpR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Sensing external and internal signals
Gene name(s): glpR
Functional conformation(s): GlpR-sn-glycerol 3-phosphate , GlpR-glycerol , GlpR
Coregulator(s): ArcA, CRP, FNR, Fis, FlhDC, GlpR, IHF
Summary: TF Summary ...[more]

REGULATION EXERTED BY CRP,GlpR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
CRP activator GlpR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
CRP-cAMP activator glpFp glpX , glpK , glpF 4118211 4118232 -60.5 ataacgctcaTTTTATGACGAGGCACACACATtttaagttcg [GEA]
[HIBSCS]
[1]
CRP-cAMP activator glpFp glpX , glpK , glpF 4118188 4118209 -37.5 cacacacattTTAAGTTCGATATTTCTCGTTTttgctcgtta [GEA]
[HIBSCS]
[1]
GlpR repressor glpFp glpX , glpK , glpF 4118169 4118188 -17.5 atttctcgttTTTGCTCGTTAACGATAAGTttacagcatg [BPP]
[HIBSCS]
[1]
GlpR repressor glpFp glpX , glpK , glpF 4118189 4118208 -37.5 acacacatttTAAGTTCGATATTTCTCGTTtttgctcgtt [BPP]
[HIBSCS]
[1]
GlpR repressor glpFp glpX , glpK , glpF 4118210 4118229 -58.5 acgctcatttTATGACGAGGCACACACATTttaagttcga [BPP]
[HIBSCS]
[1]
GlpR repressor glpFp glpX , glpK , glpF 4118231 4118250 -79.5 gatggaataaATGGCGCGATAACGCTCATTttatgacgag [BPP]
[HIBSCS]
[1]
GlpR repressor glpFp glpX , glpK , glpF 4117151 4117170 1001.5 accagctcccGCGCGGTCGTAATGGATCACgatgccaata [BPP]
[HIBSCS]
[1]
GlpR repressor glpFp glpX , glpK , glpF 4117109 4117128 1043.5 attagcgtgtCGCAGCGCGAATTTGAGCAAatctacccaa [BPP]
[HIBSCS]
[1]

Evidence: [GEA] Gene expression analysis
[HIBSCS] Human inference based on similarity to consensus sequences
[BPP] Binding of purified proteins
Reference(s): [1] Weissenborn DL., et al., 1992



Reference(s)    

 [1] Weissenborn DL., Wittekindt N., Larson TJ., 1992, Structure and regulation of the glpFK operon encoding glycerol diffusion facilitator and glycerol kinase of Escherichia coli K-12., J Biol Chem 267(9):6122-31


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