RegulonDB RegulonDB 10.6.3: Regulon Form
   
   


DnaA regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
DnaA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): chromosomal replication initiator protein DnaA, chromosomal replication initiator protein/DNA-binding transcriptional dual regulator DnaA
Gene name(s): dnaA
Functional conformation(s): DnaA , DnaA-ATP
Coregulator(s): ArcA, ArgP, CRP, CytR, DnaA, FNR, Fis, H-NS, LexA, MarA, NrdR, PurR, Rob, SoxS, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY DnaA Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
DnaA activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
DnaA-ATP activator polAp polA 4046835 4046843 -101.0 tgcacaaagtTATCCACATgacgatttgc [BPP]
[GEA]
[1]
DnaA repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
DnaA-ATP repressor yjeVp yjeV 4392677 4392685 -55.0 tctcaataaaATATCCACAgcgacgcgat [BPP]
[GEA]
[2]
DnaA-ATP repressor yjeVp yjeV 4392744 4392752 13.0 gtaaacagagTTATCCACAgcctcaggct [BPP]
[GEA]
[2]

Evidence: [BPP] Binding of purified proteins
[GEA] Gene expression analysis
Reference(s): [1] Quinones A., et al., 1997
[2] Kitagawa R., et al., 1996



Reference(s)    

 [1] Quinones A., Wandt G., Kleinstauber S., Messer W., 1997, DnaA protein stimulates polA gene expression in Escherichia coli., Mol Microbiol 23(6):1193-202

 [2] Kitagawa R., Mitsuki H., Okazaki T., Ogawa T., 1996, A novel DnaA protein-binding site at 94.7 min on the Escherichia coli chromosome., Mol Microbiol 19(5):1137-47


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