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BasR,QseB regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
QseB Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional activator QseB, QseB response regulator, YgiX
Gene name(s): qseB
Functional conformation(s): QseB , QseB-Phosphorylated
Coregulator(s): AcrR, BasR, CRP, FliZ, Fur, H-NS, HdfR, IHF, LrhA, MatA, Nac, NsrR, OmpR, PhoB, QseB, RcsB, YjjQ
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
BasR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): BasR response regulator, DNA-binding transcriptional dual regulator BasR, PmrA
Gene name(s): basR
Functional conformation(s): BasR-Phosphorylated
Coregulator(s): BasR, CRP, CpxR, Cra, CsgD, DksA, DksA-ppGpp, Fis, FliZ, H-NS, IHF, MarA, MlrA, MqsA, NagC, NanR, OmpR, PdhR, PhoP, PutA, QseB, RcdA, RcsB, RstA, SoxR, SoxS, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY BasR,QseB Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
BasR activator QseB activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
QseB-Phosphorylated activator qseBp2 qseB , qseC 3169281 3169293 -462.0 ggagcggtaaCAATTACGGATTTactttgcgga [BPP]
[GEA]
[1]
[2]
QseB-Phosphorylated activator qseBp2 qseB , qseC 3169748 3169760 6.0 ttaagggaaaAAAATAAAATTTAgtgctgtaca [BPP]
[GEA]
[1]
[2]
BasR-Phosphorylated activator qseBp2 qseB , qseC 3169726 3169745 -13.5 caagatagtcCTTAACAACTTCTTAAGGGAaaaaaataaa [BPP]
[GEA]
[3]

Evidence: [BPP] Binding of purified proteins
[GEA] Gene expression analysis
Reference(s): [1] Clarke MB., et al., 2005
[2] Clarke MB., et al., 2005
[3] Guckes KR., et al., 2013



Reference(s)    

 [1] Clarke MB., Sperandio V., 2005, Transcriptional regulation of flhDC by QseBC and sigma (FliA) in enterohaemorrhagic Escherichia coli., Mol Microbiol 57(6):1734-49

 [2] Clarke MB., Sperandio V., 2005, Transcriptional autoregulation by quorum sensing Escherichia coli regulators B and C (QseBC) in enterohaemorrhagic E. coli (EHEC)., Mol Microbiol 58(2):441-55

 [3] Guckes KR., Kostakioti M., Breland EJ., Gu AP., Shaffer CL., Martinez CR., Hultgren SJ., Hadjifrangiskou M., 2013, Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor., Proc Natl Acad Sci U S A 110(41):16592-7


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