RegulonDB RegulonDB 10.6.3: Regulon Form
   
   


H-NS,SlyA regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
H-NS      Tractordb tool
Connectivity class Global Regulator
Sensing Class TFs for DNA-bending
Synonym(s): BglY, Cur, DNA-binding protein HLP-II (HU, BH2, HD, NS), DNA-binding transcriptional dual regulator H-NS, Drc, DrdX, Drs, FimG, Hns, HnsA, Irk, MsyA, OsmZ, PilG, TopS, TopX, VirR
Gene name(s): hns
Functional conformation(s): H-NS
Coregulator(s): AcrR, AdiY, ArcA, ArgP, ArgR, BasR, CRP, CadC, CaiF, CdaR, CpxR, Cra, CsgD, CspA, CysB, DksA, DksA-ppGpp, DnaA, DpiA, EvgA, FNR, Fis, FlhDC, FliZ, Fur, GadE, GadW, GadX, GalR, GalS, GlaR, GutM, H-NS, HU, HdfR, HypT, IHF, LacI, LeuO, LrhA, Lrp, MarA, MatA, McbR, MlrA, MntR, MqsA, NagC, NanR, NarL, NarP, NhaR, NrdR, NsrR, OmpR, OxyR, PhoB, PhoP, QseB, RcdA, RcsB, Rob, RstA, RutR, SdiA, SlyA, SoxS, SrlR, StpA, SutR, TorR, UvrY, YdeO, YjjQ, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
SlyA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional dual regulator SlyA
Gene name(s): slyA
Functional conformation(s): SlyA
Coregulator(s): ArcA, CRP, FNR, Fis, Fur, H-NS, IHF, LeuO, LrhA, McbR, PaaX, PhoP, RcdA, SdiA, SlyA, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY H-NS,SlyA Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
H-NS repressor SlyA activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
SlyA activator gspCp2 gspC , gspD , gspE , gspF , gspG , gspH , gspI , gspJ , gspK , gspL , gspM , gspO 3455472 3455483 -49.5 taaatacataTTACTAATATAAataaattttg [AIBSCS]
[BPP]
[GEA]
[1]
H-NS repressor gspCp2 gspC , gspD , gspE , gspF , gspG , gspH , gspI , gspJ , gspK , gspL , gspM , gspO         [BPP]
[GEA]
[2]

Evidence: [AIBSCS] Automated inference based on similarity to consensus sequences
[BPP] Binding of purified proteins
[GEA] Gene expression analysis
Reference(s): [1] Curran T., et al., 2017
[2] Francetic O., et al., 2000



Reference(s)    

 [1] Curran T., Abacha F., Hibberd S., Rolfe M., Lacey M., Green J., 2017, Identification of new members of the Escherichia coli K-12 MG1655 SlyA regulon., Microbiology

 [2] Francetic O., Belin D., Badaut C., Pugsley AP., 2000, Expression of the endogenous type II secretion pathway in Escherichia coli leads to chitinase secretion., EMBO J 19(24):6697-703


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