RegulonDB RegulonDB 10.6.3: Regulon Form
   
   


FliZ,RstA regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
RstA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional regulator RstA, RstA response regulator, UrpT
Gene name(s): rstA
Functional conformation(s): RstA , RstA-Phosphorylated
Coregulator(s): BasR, CRP, CpxR, Cra, CsgD, EnvY, FNR, Fis, FliZ, Fur, H-NS, IHF, MlrA, MqsA, NarL, OmpR, PhoB, RcdA, RcsB, RstA, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
FliZ      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional regulator FliZ, YedH
Gene name(s): fliZ
Functional conformation(s): FliZ
Coregulator(s): AcrR, AdiY, BasR, CRP, CpxR, Cra, CsgD, EvgA, Fis, FliZ, Fur, GadE, GadW, GadX, H-NS, HdfR, IHF, LrhA, Lrp, MarA, MatA, MlrA, MqsA, OmpR, PhoP, QseB, RcdA, RcsB, RstA, RutR, TorR, YdeO, YjjQ, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY FliZ,RstA Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
FliZ repressor RstA repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
RstA-Phosphorylated repressor csgDp2 csgG , csgF , csgE , csgD 1103388 1103402 -59.5 atataacgagTTACATTTAGTTACAtgtttaacac [BPP]
[GEA]
[HIBSCS]
[1]
[2]
FliZ repressor csgDp2 csgG , csgF , csgE , csgD         [BPP]
[GEA]
[3]
[4]

Evidence: [BPP] Binding of purified proteins
[GEA] Gene expression analysis
[HIBSCS] Human inference based on similarity to consensus sequences
Reference(s): [1] Ogasawara H., et al., 2007
[2] Ogasawara H., et al., 2010
[3] Pesavento C., et al., 2008
[4] Pesavento C., et al., 2012



Reference(s)    

 [1] Ogasawara H., Hasegawa A., Kanda E., Miki T., Yamamoto K., Ishihama A., 2007, Genomic SELEX search for target promoters under the control of the PhoQP-RstBA signal relay cascade., J Bacteriol 189(13):4791-9

 [2] Ogasawara H., Yamada K., Kori A., Yamamoto K., Ishihama A., 2010, Regulation of the Escherichia coli csgD promoter: interplay between five transcription factors., Microbiology 156(Pt 8):2470-83

 [3] Pesavento C., Becker G., Sommerfeldt N., Possling A., Tschowri N., Mehlis A., Hengge R., 2008, Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli., Genes Dev 22(17):2434-46

 [4] Pesavento C., Hengge R., 2012, The global repressor FliZ antagonizes gene expression by σS-containing RNA polymerase due to overlapping DNA binding specificity., Nucleic Acids Res 40(11):4783-93


RegulonDB