RegulonDB RegulonDB 10.6.3: Regulon Form
   
   


CRP,DgoR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
CRP Weight Matrix      Tractordb tool
Connectivity class Global Regulator
Sensing Class Using internal synthesized signals
Synonym(s): Cap, Csm, DNA-binding transcriptional dual regulator CRP, GurB
Gene name(s): crp
Functional conformation(s): CRP-cAMP , CRP
Coregulator(s): AcrR, AdiY, AgaR, AraC, ArcA, ArgP, ArgR, AscG, BasR, BtsR, CRP, CaiF, ChbR, ComR, CpxR, Cra, CreB, CsgD, CspA, CsqR, CusR, CytR, DcuR, DeoR, DgoR, DksA-ppGpp, DnaA, DpiA, DsdC, EbgR, EnvY, EvgA, ExuR, FNR, FadR, FeaR, FhlA, Fis, FlhDC, FliZ, FucR, Fur, GadE, GadW, GadX, GalR, GalS, GatR, GcvA, GlaR, GlcC, GlpR, GlrR, GntR, GutM, H-NS, HU, HdfR, HipB, HprR, HyfR, HypT, IHF, IclR, IdnR, LacI, LeuO, LexA, LrhA, Lrp, LsrR, MalI, MalT, MarA, MarR, MatA, McbR, MelR, MetJ, MhpR, Mlc, MlrA, ModE, MprA, MqsA, MurR, Nac, NadR, NagC, NanR, NarL, NarP, NrdR, NsrR, NtrC, OmpR, OxyR, PaaX, PdhR, PhoB, PhoP, PrpR, PurR, PuuR, QseB, RbsR, RcdA, RcsB, RhaR, RhaS, Rob, RstA, SdiA, SlyA, SoxR, SoxS, SrlR, StpA, TdcA, TdcR, TorR, TreR, UhpA, UidR, UlaR, UvrY, UxuR, XylR, YdeO, YiaJ, YjjQ, ZraR, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
DgoR      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional regulator DgoR, YidW
Gene name(s): dgoR
Functional conformation(s): DgoR-D-galactonate , DgoR
Coregulator(s): CRP, DgoR
Summary: TF Summary ...[more]

REGULATION EXERTED BY CRP,DgoR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
CRP activator DgoR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
CRP-cAMP activator dgoRp dgoT , dgoD , dgoA , dgoK , dgoR 3875293 3875312 -117.0 attgttctttTTGTGATCTAAATTGTAGTAcaacaatata [AIBSCS]
[BPP]
[GEA]
[SM]
[1]
DgoR repressor dgoRp dgoT , dgoD , dgoA , dgoK , dgoR 3875268 3875280 -88.5 acaatataagTTTGTACTACATTacacgcacgg [AIBSCS]
[AIBSPD]
[BPP]
[GEA]
[SM]
[1]
[2]
DgoR repressor dgoRp dgoT , dgoD , dgoA , dgoK , dgoR 3875290 3875301 -110.0 tgtgatctaaATTGTAGTACAAcaatataagt [AIBSCS]
[AIBSPD]
[BPP]
[GEA]
[SM]
[1]
[2]

Evidence: [AIBSCS] Automated inference based on similarity to consensus sequences
[BPP] Binding of purified proteins
[GEA] Gene expression analysis
[SM] Site mutation
[AIBSPD] Automated inference based on sequence pattern discovery
Reference(s): [1] Belliveau NM., et al., 2018
[2] Singh B., et al., 2019



Reference(s)    

 [1] Belliveau NM., Barnes SL., Ireland WT., Jones DL., Sweredoski MJ., Moradian A., Hess S., Kinney JB., Phillips R., 2018, Systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria., Proc Natl Acad Sci U S A 115(21):E4796-E4805

 [2] Singh B., Arya G., Kundu N., Sangwan A., Nongthombam S., Chaba R., 2019, Molecular and Functional Insights into the Regulation of d-Galactonate Metabolism by the Transcriptional Regulator DgoR in Escherichia coli., J Bacteriol 201(4)


RegulonDB