RegulonDB RegulonDB 10.7: Regulon Form
   
   


NhaR,OmpR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
NhaR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External sensing using transported metabolites
Synonym(s): AntO, DNA-binding transcriptional activator NhaR, YaaB
Gene name(s): nhaR
Functional conformation(s): NhaR , NhaR-Na+
Coregulator(s): H-NS, Lrp, NhaR, OmpR, RcsB
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
OmpR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): Cry, DNA-binding transcriptional dual regulator OmpR, Kmt, OmpB, OmpR response regulator
Gene name(s): ompR
Functional conformation(s): OmpR-P , OmpR
Coregulator(s): AcrR, ArcA, BasR, CRP, CadC, CpxR, Cra, CsgD, EnvY, FNR, FadR, Fis, FliZ, Fur, GadE-RcsB, GadX, H-NS, HU, HdfR, IHF, LeuO, LrhA, Lrp, MarA, MatA, MlrA, MprA, MqsA, NhaR, OmpR, PhoB, PhoP, QseB, RcdA, RcsAB, Rob, RstA, SoxS, YjjQ, ppGpp

REGULATION EXERTED BY NhaR,OmpR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
NhaR activator OmpR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
NhaR-Na+ activator pgaAp pgaD , pgaC , pgaB , pgaA 1092578 1092594 -63.0 tcatcaggacTTTCGAAAAATCCGAAAtcatgcatcg [APIORCISFBSCS]
[BPP]
[GEA]
[1]
[2]
NhaR-Na+ activator pgaAp pgaD , pgaC , pgaB , pgaA 1092556 1092572 -41.0 cgaaatcatgCATCGGAATTTACTGATttaattattt [APIORCISFBSCS]
[BPP]
[GEA]
[1]
[2]
OmpR-P repressor pgaAp pgaD , pgaC , pgaB , pgaA 1092545 1092564 -31.5 tgcatcggaaTTTACTGATTTAATTATTTTaatcctaatt [APIORCISFBSCS]
[BPP]
[GEA]
[3]

Evidence: [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.
[BPP] Binding of purified proteins
[GEA] Gene expression analysis
Reference(s): [1] Cerca N., et al., 2008
[2] Goller C., et al., 2006
[3] Oropeza R., et al., 2015



Reference(s)    

 [1] Cerca N., Jefferson KK., 2008, Effect of growth conditions on poly-N-acetylglucosamine expression and biofilm formation in Escherichia coli., FEMS Microbiol Lett 283(1):36-41

 [2] Goller C., Wang X., Itoh Y., Romeo T., 2006, The cation-responsive protein NhaR of Escherichia coli activates pgaABCD transcription, required for production of the biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine., J Bacteriol 188(23):8022-32

 [3] Oropeza R., Salgado-Bravo R., Calva E., 2015, Deletion analysis of RcsC reveals a novel signalling pathway controlling poly-N-acetylglucosamine synthesis and biofilm formation in Escherichia coli., Microbiology 161(Pt 4):903-13


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