RegulonDB RegulonDB 10.8: Regulon Form
   
   


Nac regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
Nac Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional dual regulator Nac
Gene name(s): nac
Functional conformation(s): Nac
Coregulator(s): AdiY, ArgP, ArgR, AsnC, CRP, CytR, FNR, Fur, GadE, HdfR, IHF, Lrp, Nac, NsrR, NtrC, PhoB, PurR, QseB
Summary: TF Summary ...[more]

REGULATION EXERTED BY Nac Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
Nac activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
Nac activator gabDp1 gabD , gabT , gabP 2791121 2791135 -44.0 cggcagcgacATCAGCAATTCCTATtggtgcgcat [APIORCISFBSCS]
[CV(GEA/ROMA)]
[GEA]
[1]
[2]
Nac activator ydcSp1 ydcS , ydcT , ydcU , ydcV , patD 1511541 1511555 -51.0 cacaacctgaATAAATTTTCTCAGGggcgaaggtg [APIORCISFBSCS]
[CV(CHIP-SV/GEA/ROMA)]
[CV(GEA/ROMA)]
[GEA]
[IDA]
[3]

Evidence: [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.
[CV(GEA/ROMA)] cross validation(GEA/ROMA)
[GEA] Gene expression analysis
[CV(CHIP-SV/GEA/ROMA)] cross validation(CHIP-SV/GEA/ROMA)
[IDA] Inferred from direct assay
Reference(s): [1] Schneider BL., et al., 2002
[2] Zimmer DP., et al., 2000
[3] Schneider BL., et al., 2013



Reference(s)    

 [1] Schneider BL., Ruback S., Kiupakis AK., Kasbarian H., Pybus C., Reitzer L., 2002, The Escherichia coli gabDTPC operon: specific gamma-aminobutyrate catabolism and nonspecific induction., J Bacteriol 184(24):6976-86

 [2] Zimmer DP., Soupene E., Lee HL., Wendisch VF., Khodursky AB., Peter BJ., Bender RA., Kustu S., 2000, Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation., Proc Natl Acad Sci U S A 97(26):14674-9

 [3] Schneider BL., Hernandez VJ., Reitzer L., 2013, Putrescine catabolism is a metabolic response to several stresses in Escherichia coli., Mol Microbiol 88(3):537-50


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