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LexA,RcdA regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
LexA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional repressor LexA, ExrA, Spr, Tsl, UmuA
Gene name(s): lexA
Functional conformation(s): LexA
Coregulator(s): ArcA, CRP, DinJ-YafQ, DnaA, LexA, NagC, RcdA, RcsB-BglJ, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
RcdA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional regulator RcdA, YbjK
Gene name(s): rcdA
Functional conformation(s): RcdA
Coregulator(s): ArcA, BasR, BtsR, CRP, CpxR, Cra, CsgD, FliZ, H-NS, IHF, LexA, McbR, MlrA, MqsA, OmpR, PhoB, RcdA, RcsAB, RstA, SdiA, SlyA, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY LexA,RcdA Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
LexA repressor RcdA repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
LexA repressor sulAp sulA 1020942 1020961 -5.0 tcactggatgTACTGTACATCCATACAGTAactcacaggg [BCE] [1]
RcdA repressor sulAp sulA 1020910 1020920 33.5 ctggattgatTATGTACACTTcaggctatgc [APIORCISFBSCS]
[BPP]
[CV(GEA)]
[CV(GEA)]
[GEA]
[2]
RcdA repressor sulAp sulA 1020896 1020906 47.5 tacacttcagGCTATGCACATcgttcttcgt [APIORCISFBSCS]
[BPP]
[CV(GEA)]
[CV(GEA)]
[GEA]
[2]

Evidence: [BCE] Binding of cellular extracts
[APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.
[BPP] Binding of purified proteins
[CV(GEA)] cross validation(GEA)
[GEA] Gene expression analysis
Reference(s): [1] Mizusawa S., et al., 1983
[2] Shimada T., et al., 2012



Reference(s)    

 [1] Mizusawa S., Court D., Gottesman S., 1983, Transcription of the sulA gene and repression by LexA., J Mol Biol 171(3):337-43

 [2] Shimada T., Katayama Y., Kawakita S., Ogasawara H., Nakano M., Yamamoto K., Ishihama A., 2012, A novel regulator RcdA of the csgD gene encoding the master regulator of biofilm formation in Escherichia coli., Microbiologyopen 1(4):381-94


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