RegulonDB

TRANSCRIPTION FACTOR:

Name:

LexA	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional repressor LexA, ExrA, Spr, Tsl, UmuA

Gene name(s):

lexA

Functional conformation(s):

LexA

Coregulator(s):

ArcA, CRP, DinJ-YafQ, DnaA, LexA, NagC, RcdA, RcsB-BglJ, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Name:

RcdA	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

DNA-binding transcriptional regulator RcdA, YbjK

Gene name(s):

rcdA

Functional conformation(s):

RcdA

Coregulator(s):

ArcA, BasR, BtsR, CRP, CpxR, Cra, CsgD, FliZ, H-NS, IHF, LexA, McbR, MlrA, MqsA, OmpR, PhoB, RcdA, RcsAB, RstA, SdiA, SlyA, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY LexA,RcdA

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
LexA repressor RcdA repressor
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
LexA	repressor	sulAp	sulA	1020942	1020961	-5.0	tcactggatgTACTGTACATCCATACAGTAactcacaggg	[BCE]	[1]
RcdA	repressor	sulAp	sulA	1020910	1020920	33.5	ctggattgatTATGTACACTTcaggctatgc	[APIORCISFBSCS] [BPP] [CV(GEA)] [CV(GEA)] [GEA]	[2]
RcdA	repressor	sulAp	sulA	1020896	1020906	47.5	tacacttcagGCTATGCACATcgttcttcgt	[APIORCISFBSCS] [BPP] [CV(GEA)] [CV(GEA)] [GEA]	[2]

Evidence:	[BCE] Binding of cellular extracts [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence. [BPP] Binding of purified proteins [CV(GEA)] cross validation(GEA) [GEA] Gene expression analysis
Reference(s):	[1] Mizusawa S., et al., 1983 [2] Shimada T., et al., 2012

Reference(s)
[1] Mizusawa S., Court D., Gottesman S., 1983, Transcription of the sulA gene and repression by LexA., J Mol Biol 171(3):337-43
[2] Shimada T., Katayama Y., Kawakita S., Ogasawara H., Nakano M., Yamamoto K., Ishihama A., 2012, A novel regulator RcdA of the csgD gene encoding the master regulator of biofilm formation in Escherichia coli., Microbiologyopen 1(4):381-94