RegulonDB RegulonDB 10.8: Regulon Form
   
   


RcsAB regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
RcsAB Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): RcsAB DNA-binding transcriptional dual regulator
Gene name(s): rcsA, rcsB
Functional conformation(s): RcsAB
Coregulator(s): AcrR, BasR, BtsR, CRP, CpxR, Cra, CsgD, FliZ, Fur, GadE, H-NS, HdfR, IHF, LrhA, MatA, MlrA, MqsA, OmpR, QseB, RcdA, RcsAB, RstA, YjjQ, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY RcsAB Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
RcsAB activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
RcsAB activator wzap wcaB , wcaA , wzc , wzb , wza 2137659 2137673 -83.0 taaaaaccatATTGAATGACACTTAatataattct [AIBSCS]
[CV(GEA)]
[GEA]
[1]
RcsAB activator wzap wcaB , wcaA , wzc , wzb , wza 2137681 2137695 -105.0 attgtcaaccTAAAGAAACTCCTAAaaaccatatt [BPP]
[CV(SM)]
[SM]
[2]
[3]
[4]

Evidence: [AIBSCS] Automated inference based on similarity to consensus sequences
[CV(GEA)] cross validation(GEA)
[GEA] Gene expression analysis
[BPP] Binding of purified proteins
[CV(SM)] cross validation(SM)
[SM] Site mutation
Reference(s): [1] Ebel W., et al., 1999
[2] Gottesman S., et al., 1991
[3] Stout V. 1996
[4] Wehland M., et al., 2000



Reference(s)    

 [1] Ebel W., Trempy JE., 1999, Escherichia coli RcsA, a positive activator of colanic acid capsular polysaccharide synthesis, functions To activate its own expression., J Bacteriol 181(2):577-84

 [2] Gottesman S., Stout V., 1991, Regulation of capsular polysaccharide synthesis in Escherichia coli K12., Mol Microbiol 5(7):1599-606

 [3] Stout V., 1996, Identification of the promoter region for the colanic acid polysaccharide biosynthetic genes in Escherichia coli K-12., J Bacteriol 178(14):4273-80

 [4] Wehland M., Bernhard F., 2000, The RcsAB box. Characterization of a new operator essential for the regulation of exopolysaccharide biosynthesis in enteric bacteria., J Biol Chem 275(10):7013-20


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