RegulonDB RegulonDB 10.8: Regulon Form
   
   


LexA,RcsB-BglJ regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
LexA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional repressor LexA, ExrA, Spr, Tsl, UmuA
Gene name(s): lexA
Functional conformation(s): LexA
Coregulator(s): ArcA, CRP, DinJ-YafQ, DnaA, LexA, NagC, RcdA, RcsB-BglJ, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
RcsB-BglJ      Tractordb tool
Connectivity class Local Regulator
Synonym(s): RcsB-BglJ DNA-binding transcriptional activator, RcsBgl
Gene name(s): bglJ, rcsB
Functional conformation(s): RcsB-BglJ
Coregulator(s): CRP, Fis, H-NS, LeuO, LexA, RcsB-BglJ, StpA
Summary: TF Summary ...[more]

REGULATION EXERTED BY LexA,RcsB-BglJ Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
LexA repressor RcsB-BglJ activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
LexA repressor yehFp yehF 2196446 2196465 11.5 catctgcattCAACTGGATAAAATTACAGGgatgcagaat [AIBSCS] [1]
RcsB-BglJ activator yehFp yehF 2196369 2196389 -66.5 agcgccttttCTTTATAAATTCCTAAAGTTGttttcttgcg [AIBSCS]
[CV(GEA)]
[GEA]
[2]

Evidence: [AIBSCS] Automated inference based on similarity to consensus sequences
[CV(GEA)] cross validation(GEA)
[GEA] Gene expression analysis
Reference(s): [1] Fernandez De Henestrosa AR., et al., 2000
[2] Salscheider SL., et al., 2014



Reference(s)    

 [1] Fernandez De Henestrosa AR., Ogi T., Aoyagi S., Chafin D., Hayes JJ., Ohmori H., Woodgate R., 2000, Identification of additional genes belonging to the LexA regulon in Escherichia coli., Mol Microbiol 35(6):1560-72

 [2] Salscheider SL., Jahn A., Schnetz K., 2014, Transcriptional regulation by BglJ-RcsB, a pleiotropic heteromeric activator in Escherichia coli., Nucleic Acids Res 42(5):2999-3008


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