RegulonDB

TRANSCRIPTION FACTOR:

Name:

LexA	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional repressor LexA, ExrA, Spr, Tsl, UmuA

Gene name(s):

lexA

Functional conformation(s):

LexA

Coregulator(s):

ArcA, CRP, DinJ-YafQ, DnaA, LexA, NagC, RcdA, RcsB-BglJ, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Name:

RcsB-BglJ

Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

RcsB-BglJ DNA-binding transcriptional activator, RcsBgl

Gene name(s):

bglJ, rcsB

Functional conformation(s):

RcsB-BglJ

Coregulator(s):

CRP, Fis, H-NS, LeuO, LexA, RcsB-BglJ, StpA

Summary:

TF Summary ...[more]

REGULATION EXERTED BY LexA,RcsB-BglJ

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
LexA repressor RcsB-BglJ activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
LexA	repressor	yehFp	yehF	2196446	2196465	11.5	catctgcattCAACTGGATAAAATTACAGGgatgcagaat	[AIBSCS]	[1]
RcsB-BglJ	activator	yehFp	yehF	2196369	2196389	-66.5	agcgccttttCTTTATAAATTCCTAAAGTTGttttcttgcg	[AIBSCS] [CV(GEA)] [GEA]	[2]

Evidence:	[AIBSCS] Automated inference based on similarity to consensus sequences [CV(GEA)] cross validation(GEA) [GEA] Gene expression analysis
Reference(s):	[1] Fernandez De Henestrosa AR., et al., 2000 [2] Salscheider SL., et al., 2014

Reference(s)
[1] Fernandez De Henestrosa AR., Ogi T., Aoyagi S., Chafin D., Hayes JJ., Ohmori H., Woodgate R., 2000, Identification of additional genes belonging to the LexA regulon in Escherichia coli., Mol Microbiol 35(6):1560-72
[2] Salscheider SL., Jahn A., Schnetz K., 2014, Transcriptional regulation by BglJ-RcsB, a pleiotropic heteromeric activator in Escherichia coli., Nucleic Acids Res 42(5):2999-3008