RegulonDB RegulonDB 10.8: Regulon Form
   
   


PyrR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
PyrR      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional activator PyrR, YpdB
Gene name(s): pyrR
Functional conformation(s): PyrR , PyrR-Pasp , PyrR-BTS
Coregulator(s): PyrR
Summary: TF Summary ...[more]

REGULATION EXERTED BY PyrR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
PyrR activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
PyrR-BTS activator yhjXp yhjX 3712091 3712101 -52.5 tccgttctgaTGGCATTTCATgccgtttttc [BPP]
[CV(GEA)]
[CV(GEA)]
[CV(GEA/GS)]
[CV(GEA/GS)]
[CV(GEA/SM)]
[CV(GEA/SM/GS)]
[CV(SM)]
[GEA]
[GS]
[SM]
[1]
[2]
PyrR-BTS activator yhjXp yhjX 3712112 3712122 -73.5 tcctgaactaAGGCATTTCATtccgttctga [BPP]
[CV(GEA)]
[CV(GEA)]
[CV(GEA/GS)]
[CV(GEA/GS)]
[CV(GEA/SM)]
[CV(GEA/SM/GS)]
[CV(SM)]
[GEA]
[GS]
[SM]
[1]
[2]

Evidence: [BPP] Binding of purified proteins
[CV(GEA)] cross validation(GEA)
[CV(GEA/GS)] cross validation(GEA/GS)
[CV(GEA/SM)] cross validation(GEA/SM)
[CV(GEA/SM/GS)] cross validation(GEA/SM/GS)
[CV(SM)] cross validation(SM)
[GEA] Gene expression analysis
[GS] genomic SELEX
[SM] Site mutation
Reference(s): [1] Fried L., et al., 2013
[2] Miyake Y., et al., 2019



Reference(s)    

 [1] Fried L., Behr S., Jung K., 2013, Identification of a Target Gene and Activating Stimulus for the YpdA/YpdB Histidine Kinase/Response Regulator System in Escherichia coli., J Bacteriol 195(4):807-15

 [2] Miyake Y., Inaba T., Watanabe H., Teramoto J., Yamamoto K., Ishihama A., 2019, Regulatory roles of pyruvate-sensing two-component system PyrSR (YpdAB) in Escherichia coli K-12., FEMS Microbiol Lett 366(2)


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