RegulonDB RegulonDB 10.9: Regulon Form
   
   


MraZ,PdhR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
PdhR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): AceC, DNA-binding transcriptional dual regulator PdhR, GenA, YacB
Gene name(s): pdhR
Functional conformation(s): PdhR-pyruvate , PdhR
Coregulator(s): ArcA, AscG, BasR, BtsR, CRP, CpxR, Cra, CusR, FNR, Fis, Fur, GadE, GlcC, HprR, HypT, IHF, MraZ, NsrR, PdhR, PhoP
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
MraZ Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional repressor MraZ, YabB
Gene name(s): mraZ
Functional conformation(s): MraZ
Coregulator(s): MraZ, PdhR, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY MraZ,PdhR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
MraZ repressor PdhR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
PdhR repressor mraZp mraZ , rsmH , ftsL , ftsI , murE , murF , mraY , murD , ftsW , murG , murC , ddlB , ftsQ , ftsA , ftsZ , lpxC 89546 89562 -42.0 tatgccttgtGACTGGCTTGACAAGCTTttcctcagct   [1]
MraZ repressor mraZp mraZ , rsmH , ftsL , ftsI , murE , murF , mraY , murD , ftsW , murG , murC , ddlB , ftsQ , ftsA , ftsZ , lpxC 89591 89595 -3.0 ctcctttcagTGGGAAattgtggggc   [2]
MraZ repressor mraZp mraZ , rsmH , ftsL , ftsI , murE , murF , mraY , murD , ftsW , murG , murC , ddlB , ftsQ , ftsA , ftsZ , lpxC 89601 89605 8.0 tgggaaattgTGGGGCaaagtgggaa   [2]
MraZ repressor mraZp mraZ , rsmH , ftsL , ftsI , murE , murF , mraY , murD , ftsW , murG , murC , ddlB , ftsQ , ftsA , ftsZ , lpxC 89611 89615 18.0 tggggcaaagTGGGAAtaaggggtga   [2]

Reference(s): [1] Gohler AK., et al., 2011
[2] Eraso JM., et al., 2014



Reference(s)    

 [1] Gohler AK., Kokpinar O., Schmidt-Heck W., Geffers R., Guthke R., Rinas U., Schuster S., Jahreis K., Kaleta C., 2011, More than just a metabolic regulator - elucidation and validation of new targets of PdhR in Escherichia coli., BMC Syst Biol 5(1):197

 [2] Eraso JM., Markillie LM., Mitchell HD., Taylor RC., Orr G., Margolin W., 2014, The Highly Conserved MraZ Protein Is a Transcriptional Regulator in Escherichia coli., J Bacteriol 196(11):2053-66


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