RegulonDB RegulonDB 10.9: Regulon Form
   
   


MngR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
MngR      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional repressor MngR, FarR, YbgB
Gene name(s): mngR
Functional conformation(s): MngR
Coregulator(s): MngR
Summary: TF Summary ...[more]

REGULATION EXERTED BY MngR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
MngR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
MngR repressor mngRp mngR 765934 765955 -18.5 ttgattgaaaTTATTTGTATTGTATTTGTATTAtttacaggat   [1]
MngR repressor mngRp mngR 765890 765911 26.5 aatttatcggGCATAATGGTTAAATTCGTATTAatgagatact   [1]
MngR repressor mngAp mngA , mngB 765890 765911 90.5 agtatctcatTAATACGAATTTAACCATTATGCccgataaatt [APIORCISFBSCS]
[BPP]
[2]
[1]
MngR repressor mngAp mngA , mngB 765934 765955 134.5 atcctgtaaaTAATACAAATACAATACAAATAAtttcaatcaa [APIORCISFBSCS]
[BPP]
[2]
[1]

Evidence: [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.
[BPP] Binding of purified proteins
Reference(s): [1] Sampaio MM., et al., 2004
[2] Quail MA., et al., 1994



Reference(s)    

 [1] Sampaio MM., Chevance F., Dippel R., Eppler T., Schlegel A., Boos W., Lu YJ., Rock CO., 2004, Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor., J Biol Chem 279(7):5537-48

 [2] Quail MA., Dempsey CE., Guest JR., 1994, Identification of a fatty acyl responsive regulator (FarR) in Escherichia coli., FEBS Lett 356(2-3):183-7


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