RegulonDB RegulonDB 10.10: Regulon Form
   
   


RcsB regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
RcsB Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional activator RcsB, RcsB response regulator
Gene name(s): rcsB
Functional conformation(s): RcsB-phosphorylated , RcsB , RcsB-acetylated
Coregulator(s): AdiY, ArcA, CRP, CadC, CpxR, EvgA, FNR, Fis, FliZ, GadE, GadE-RcsB, GadW, GadX, GlrR, H-NS, LeuO, LexA, Lrp, MarA, NagC, NarL, NarP, NhaR, NtrC, OmpR, PhoB, PhoP, RcsB, RcsB-BglJ, Rob, SdiA, StpA, TorR, UvrY, YdeO, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY RcsB Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
RcsB activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
RcsB-phosphorylated activator osmBp1 osmB 1343511 1343524 -41.5 ggttgataatTAAGACTATTTACCtgttattaac [GEA] [1]
RcsB-phosphorylated activator bdmp sra , bdm 1556375 1556388 -41.5 aatcatcaacCAGGACTAATCTTAacaacgaagc [GEA] [2]
RcsB-phosphorylated activator ftsAp1 ftsA , ftsZ 103511 103524 -43.5 ctgatgaattGAAGATTCATCTGGttgaatatgt [GEA] [3]
RcsB-phosphorylated activator lolAp lolA , rarA 937278 937291 -43.5 aactgaaaatTCAGTATTTTCTTCtttcctcaag [GEA] [4]

Evidence: [GEA] Gene expression analysis
Reference(s): [1] Boulanger A., et al., 2005
[2] Francez-Charlot A., et al., 2005
[3] Carballes F., et al., 1999
[4] Tao K., et al., 2012



Reference(s)    

 [1] Boulanger A., Francez-Charlot A., Conter A., Castanie-Cornet MP., Cam K., Gutierrez C., 2005, Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay., J Bacteriol 187(9):3282-6

 [2] Francez-Charlot A., Castanie-Cornet MP., Gutierrez C., Cam K., 2005, Osmotic regulation of the Escherichia coli bdm (biofilm-dependent modulation) gene by the RcsCDB His-Asp phosphorelay., J Bacteriol 187(11):3873-7

 [3] Carballes F., Bertrand C., Bouche JP., Cam K., 1999, Regulation of Escherichia coli cell division genes ftsA and ftsZ by the two-component system rcsC-rcsB., Mol Microbiol 34(3):442-50

 [4] Tao K., Narita S., Tokuda H., 2012, Defective lipoprotein sorting induces lolA expression through the Rcs stress response phosphorelay system., J Bacteriol 194(14):3643-50


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