RegulonDB

TRANSCRIPTION FACTOR:

Name:

FadR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional dual regulator FadR, Dec, Ole, OleR, ThdB

Gene name(s):

fadR

Functional conformation(s):

FadR-an acyl-CoA , FadR

Coregulator(s):

ArcA, CRP, DksA-ppGpp, FabR, FadR, Fis, HipB, IHF, IclR, OmpR, PhoP, Rob, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Name:

IclR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional repressor IclR

Gene name(s):

iclR

Functional conformation(s):

IclR-glyoxylate , IclR , IclR-pyruvate

Coregulator(s):

ArcA, CRP, Cra, FadR, IHF, IclR

Summary:

TF Summary ...[more]

REGULATION EXERTED BY FadR,IclR

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
FadR activator IclR repressor
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
FadR	activator	iclRp	iclR	4223698	4223714	-54.0	gttcaacattAACTCATCGGATCAGTTcagtaactat	[GEA]	[1]
IclR-pyruvate	repressor	iclRp	iclR	4223652	4223667	-7.0	aacaataaaaATGAAAATGATTTCCAcgatacagaa	[GEA]	[2]

Evidence:	[GEA] Gene expression analysis
Reference(s):	[1] Gui L., et al., 1996 [2] Yamamoto K., et al., 2003

Reference(s)
[1] Gui L., Sunnarborg A., LaPorte DC., 1996, Regulated expression of a repressor protein: FadR activates iclR., J Bacteriol 178(15):4704-9
[2] Yamamoto K., Ishihama A., 2003, Two different modes of transcription repression of the Escherichia coli acetate operon by IclR., Mol Microbiol 47(1):183-94