RegulonDB

TRANSCRIPTION FACTOR:

Name:

FadR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional dual regulator FadR, Dec, Ole, OleR, ThdB

Gene name(s):

fadR

Functional conformation(s):

FadR-an acyl-CoA , FadR

Coregulator(s):

ArcA, CRP, DksA-ppGpp, FabR, FadR, Fis, HipB, IHF, IclR, OmpR, PhoP, Rob, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

IHF	Weight Matrix Tractordb tool

Connectivity class

Global Regulator

Sensing Class

TFs for DNA-bending

Synonym(s):

DNA-binding transcriptional dual regulator IHF

Gene name(s):

ihfB, ihfA

Functional conformation(s):

IHF

Coregulator(s):

AcrR, AdiY, ArcA, ArgR, AtoC, BasR, BolA, BtsR, CRP, Cbl, CpxR, Cra, CsgD, CysB, DksA, DksA-ppGpp, EnvY, FNR, FadR, FhlA, Fis, FlhDC, FliZ, Fur, GadE, GlcC, GlpR, GlrR, H-NS, HU, HdfR, HipAB, HipB, IHF, IclR, IscR, LrhA, Lrp, MarA, MatA, MlrA, MntR, ModE, MprA, MqsA, Nac, NagC, NanR, NarL, NarP, NorR, NsrR, NtrC, OmpR, OxyR, PaaX, PdhR, PepA, PhoB, PlaR, PspF, PurR, QseB, RcdA, RcsAB, Rob, RstA, RtcR, RutR, SlyA, SoxR, SoxS, SutR, TdcA, TdcR, TrpR, TyrR, UlaR, UvrY, YeiL, YjjQ, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY FadR,IHF,ppGpp

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
FadR repressor IHF activator ppGpp activation
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
FadR	repressor	uspAp1	uspA	3640071	3640087	97.0	agaaacgctaGCTGGCCAGTCATCGACaactttatgg	[GEA]	[1]
FadR	repressor	uspAp1	uspA	3639979	3639995	5.0	ctataaggtaAGGATGGTCTTAACACTgaatctttac	[GEA]	[1]
IHF	activator	uspAp1	uspA	3639896	3639908	-81.0	ggttaaccacTATCAATATATTCatgtcgaaaa	[GEA]	[2] [3]

Evidence:	[GEA] Gene expression analysis
Reference(s):	[1] Farewell A., et al., 1996 [2] Farewell A., et al., 1998 [3] Nystrom T. 1995

Reference(s)
[1] Farewell A., Diez AA., DiRusso CC., Nystrom T., 1996, Role of the Escherichia coli FadR regulator in stasis survival and growth phase-dependent expression of the uspA, fad, and fab genes., J Bacteriol 178(22):6443-50
[2] Farewell A., Kvint K., Nystrom T., 1998, uspB, a new sigmaS-regulated gene in Escherichia coli which is required for stationary-phase resistance to ethanol., J Bacteriol 180(23):6140-7
[3] Nystrom T., 1995, Glucose starvation stimulon of Escherichia coli: role of integration host factor in starvation survival and growth phase-dependent protein synthesis., J Bacteriol 177(19):5707-10