RegulonDB

TRANSCRIPTION FACTOR:

Name:

FadR	Weight Matrix Tractordb tool

Connectivity class

Local Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

DNA-binding transcriptional dual regulator FadR, Dec, Ole, OleR, ThdB

Gene name(s):

fadR

Functional conformation(s):

FadR-an acyl-CoA , FadR

Coregulator(s):

ArcA, CRP, DksA-ppGpp, FabR, FadR, Fis, HipB, IHF, IclR, OmpR, PhoP, Rob, ppGpp

Summary:

TF Summary ...[more]

REGULATION EXERTED BY FadR

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
FadR activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
FadR	activator	fabIp	fabI	1351161	1351177	-48.0	ccgcagcctgCTCCGGTCGGACCTGGCaactatagct	[GEA]	[1]
FadR	activator	accAp2	accA	208280	208296	-38.0	atcgtcagcgGACAGGTCAGCTTTGATgacttcagcg	[GEA]	[1]
FadR	activator	accBp2	accB , accC	3405115	3405131	-49.0	tgattatcttCCCTGATAAGACCAGTAtttagctgcc	[GEA]	[1]
FadR	activator	accDp	accD	2434056	2434072	-49.0	aaaagtaactCCGCGGTTCGACCACTTttttatccaa	[GEA]	[1]
FadR repressor
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
FadR	repressor	fadMp1	fadM	464353	464369	2.0	aagaggtcatACCAGTTATGACCTCTGtacttataac		[2]

Evidence:	[GEA] Gene expression analysis
Reference(s):	[1] My L., et al., 2015 [2] Nie L., et al., 2008

Reference(s)
[1] My L., Ghandour Achkar N., Viala JP., Bouveret E., 2015, Reassessment of the Genetic Regulation of Fatty Acid Synthesis in Escherichia coli: Global Positive Control by the Dual Functional Regulator FadR., J Bacteriol 197(11):1862-72
[2] Nie L., Ren Y., Schulz H., 2008, Identification and characterization of Escherichia coli thioesterase III that functions in fatty acid beta-oxidation., Biochemistry 47(29):7744-51