RegulonDB RegulonDB 10.10: Regulon Form
   
   


FadR regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
FadR Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional dual regulator FadR, Dec, Ole, OleR, ThdB
Gene name(s): fadR
Functional conformation(s): FadR-an acyl-CoA , FadR
Coregulator(s): ArcA, CRP, DksA-ppGpp, FabR, FadR, Fis, HipB, IHF, IclR, OmpR, PhoP, Rob, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY FadR Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
FadR activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
FadR activator fabIp fabI 1351161 1351177 -48.0 ccgcagcctgCTCCGGTCGGACCTGGCaactatagct [GEA] [1]
FadR activator accAp2 accA 208280 208296 -38.0 atcgtcagcgGACAGGTCAGCTTTGATgacttcagcg [GEA] [1]
FadR activator accBp2 accB , accC 3405115 3405131 -49.0 tgattatcttCCCTGATAAGACCAGTAtttagctgcc [GEA] [1]
FadR activator accDp accD 2434056 2434072 -49.0 aaaagtaactCCGCGGTTCGACCACTTttttatccaa [GEA] [1]
FadR repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
FadR repressor fadMp1 fadM 464353 464369 2.0 aagaggtcatACCAGTTATGACCTCTGtacttataac   [2]

Evidence: [GEA] Gene expression analysis
Reference(s): [1] My L., et al., 2015
[2] Nie L., et al., 2008



Reference(s)    

 [1] My L., Ghandour Achkar N., Viala JP., Bouveret E., 2015, Reassessment of the Genetic Regulation of Fatty Acid Synthesis in Escherichia coli: Global Positive Control by the Dual Functional Regulator FadR., J Bacteriol 197(11):1862-72

 [2] Nie L., Ren Y., Schulz H., 2008, Identification and characterization of Escherichia coli thioesterase III that functions in fatty acid beta-oxidation., Biochemistry 47(29):7744-51


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