RegulonDB RegulonDB 10.10: Regulon Form
   
   


LexA,NagC regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
NagC Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External sensing using transported metabolites
Synonym(s): DNA-binding transcriptional dual regulator NagC, NagR, transcriptional repressor of nag (N-acetylglucosamine) operon
Gene name(s): nagC
Functional conformation(s): NagC , NagC-N-acetyl-D-glucosamine 6-phosphate
Coregulator(s): AraC, BasR, CRP, ChbR, Cra, DksA, DksA-ppGpp, EvgA, FNR, Fur, GadX, GalR, GalS, H-NS, IHF, LexA, Mlc, NagC, NanR, NarL, NarP, OmpR, PhoP, RcsB, UvrY, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
LexA Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class Using internal synthesized signals
Synonym(s): DNA-binding transcriptional repressor LexA, ExrA, Spr, Tsl, UmuA
Gene name(s): lexA
Functional conformation(s): LexA
Coregulator(s): ArcA, CRP, DinJ-YafQ, DnaA, LexA, NagC, RcdA, RcsB-BglJ, ppGpp
Summary: TF Summary ...[more]

REGULATION EXERTED BY LexA,NagC Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
LexA repressor NagC repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
NagC repressor dinIp dinI 1121512 1121534 -14.0 ttgtcattagGTTATTTTACCTGTATAAATAACcagtatattc    
LexA repressor dinIp dinI 1121507 1121526 -7.5 aggttattttACCTGTATAAATAACCAGTAtattcaacag [GEA] [1]
[2]

Evidence: [GEA] Gene expression analysis
Reference(s): [1] Lewis LK., et al., 1994
[2] Yasuda T., et al., 1996



Reference(s)    

 [1] Lewis LK., Harlow GR., Gregg-Jolly LA., Mount DW., 1994, Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli., J Mol Biol 241(4):507-23

 [2] Yasuda T., Nagata T., Ohmori H., 1996, Multicopy suppressors of the cold-sensitive phenotype of the pcsA68 (dinD68) mutation in Escherichia coli., J Bacteriol 178(13):3854-9


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