RegulonDB

TRANSCRIPTION FACTOR:

Name:

ZraR	Tractordb tool

Connectivity class

Local Regulator

Sensing Class

External-Two-component systems

Synonym(s):

DNA-binding transcriptional activator ZraR, HydG, ZraR response regulator

Gene name(s):

zraR

Functional conformation(s):

ZraR , ZraR-phosphorylated

Coregulator(s):

CRP, ZraR

Summary:

TF Summary ...[more]

REGULATION EXERTED BY ZraR

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
ZraR activator
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
ZraR-phosphorylated	activator	zraPp	zraP	4201811	4201827	-107.0	aagtttcaatGAGTAAAAATGACTCGCtacccgcagc	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1] [2]
ZraR-phosphorylated	activator	zraPp	zraP	4201782	4201798	-78.0	cccgcagcagGCGAGTCATTTTTACTCgtttatcatg	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1] [2]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s):	[1] Leonhartsberger S., et al., 2001 [2] Rome K., et al., 2018

Reference(s)
[1] Leonhartsberger S., Huber A., Lottspeich F., Bock A., 2001, The hydH/G Genes from Escherichia coli code for a zinc and lead responsive two-component regulatory system., J Mol Biol 307(1):93-105
[2] Rome K., Borde C., Taher R., Cayron J., Lesterlin C., Gueguen E., De Rosny E., Rodrigue A., 2018, The Two-Component System ZraPSR Is a Novel ESR that Contributes to Intrinsic Antibiotic Tolerance in Escherichia coli., J Mol Biol 430(24):4971-4985