RegulonDB RegulonDB 11.2: Regulon Form
   
   


AlpA,PhoB regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
PhoB Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Sensing Class External-Two-component systems
Synonym(s): DNA-binding transcriptional dual regulator PhoB, PhoB response regulator, PhoT
Gene name(s): phoB
Functional conformation(s): PhoB , PhoB-phosphorylated
Coregulator(s): AlpA, ArgP, AscG, CRP, CpxR, CusR, EnvY, FNR, Fur, GadE, GadE-RcsB, GadW, GadX, H-NS, HprR, IHF, Nac, NsrR, OmpR, PhoB, PrpR, QseB, RcdA, RstA, RutR
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
AlpA      Tractordb tool
Connectivity class Local Regulator
Synonym(s): CP4-57 prophage; DNA-binding transcriptional activator AlpA
Gene name(s): alpA
Functional conformation(s): AlpA
Coregulator(s): AlpA, PhoB
Summary: TF Summary ...[more]

REGULATION EXERTED BY AlpA,PhoB Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
AlpA repressor PhoB activator    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
PhoB-phosphorylated activator phoBp phoB , phoR 417061 417079 -31.0 tgcgacgagcTTTTCATAAATCTGTCATAaatctgacgc [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
AlpA repressor phoBp phoB , phoR

Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s): [1] Marzan LW., et al., 2013
[2] Yang C., et al., 2012



Reference(s)    

 [1] Marzan LW., Hasan CM., Shimizu K., 2013, Effect of acidic condition on the metabolic regulation of Escherichia coli and its phoB mutant., Arch Microbiol 195(3):161-71

 [2] Yang C., Huang TW., Wen SY., Chang CY., Tsai SF., Wu WF., Chang CH., 2012, Genome-wide PhoB binding and gene expression profiles reveal the hierarchical gene regulatory network of phosphate starvation in Escherichia coli., PLoS One 7(10):e47314

 [3] Song S., Kim JS., Yamasaki R., Oh S., Benedik MJ., Wood TK., 2021, Escherichia coli cryptic prophages sense nutrients to influence persister cell resuscitation., Environ Microbiol 23(11):7245-7254

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