RegulonDB RegulonDB 11.1: Regulon Form
   
   


CsgD,FlhDC,PdeL regulon in Escherichia coli K-12 genome


TRANSCRIPTION FACTOR: Info
Name:
CsgD Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional dual regulator CsgD
Gene name(s): csgD
Functional conformation(s): CsgD
Coregulator(s): BasR, BolA, BtsR, CRP, CpxR, Cra, CsgD, DksA-ppGpp, FlhDC, FliZ, H-NS, IHF, MatA, MlrA, MqsA, NsrR, OmpR, PdeL, RcdA, RcsAB, RstA, SutR, ppGpp
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
PdeL      Tractordb tool
Connectivity class Local Regulator
Synonym(s): DNA-binding transcriptional regulator/c-di-GMP phosphodiesterase PdeL, YahA
Gene name(s): pdeL
Functional conformation(s): PdeL
Coregulator(s): CsgD, FlhDC, PdeL
Summary: TF Summary ...[more]
TRANSCRIPTION FACTOR: Info
Name:
FlhDC Weight Matrix      Tractordb tool
Connectivity class Local Regulator
Synonym(s): FlhDC DNA-binding transcriptional dual regulator
Gene name(s): flhC, flhD
Functional conformation(s): FlhDC
Coregulator(s): ArcA, BtsR, CRP, CsgD, DpiA, FNR, FhlA, Fis, FlhDC, GalR, GalS, GlpR, H-NS, IHF, MatA, ModE, NarL, NarP, NsrR, PdeL, SutR
Summary: TF Summary ...[more]

REGULATION EXERTED BY CsgD,FlhDC,PdeL Info M3D | Colombos
KNOWN BINDING SITES (The central relative position is relative to the promoter +1)    
CsgD repressor FlhDC activator PdeL repressor    
Transcription Factor
Regulated
Binding Sites
Evidence
References
Functional conformation
Function
Promoter
Gene(s)
LeftPos
RigthPos
Central Rel-Pos
Sequence
FlhDC activator fliFp1 fliF , fliG , fliH , fliI , fliJ , fliK 2013068 2013086 -69.5 gtcaataagaCAAAGGCGCTAAATAGCAAcaaaaaaacg [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
FlhDC activator fliFp1 fliF , fliG , fliH , fliI , fliJ , fliK 2013097 2013113 -41.0 caaaaaaacgGGTTTATTGGCGGATAGaaaaaaacga [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [1]
[2]
CsgD repressor fliFp1 fliF , fliG , fliH , fliI , fliJ , fliK 2013069 2013083 -70.5 tcaataagacAAAGGCGCTAAATAGcaacaaaaaa [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [3]
CsgD repressor fliFp1 fliF , fliG , fliH , fliI , fliJ , fliK 2013054 2013068 -85.5 aagcctaccaGTAAGTCAATAAGACaaaggcgcta [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [3]
PdeL repressor fliFp1 fliF , fliG , fliH , fliI , fliJ , fliK

Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s): [1] Stafford GP., et al., 2005
[2] Yilmaz C., et al., 2020
[3] Ogasawara H., et al., 2011



Reference(s)    

 [1] Stafford GP., Ogi T., Hughes C., 2005, Binding and transcriptional activation of non-flagellar genes by the Escherichia coli flagellar master regulator FlhD2C2., Microbiology 151(Pt 6):1779-88

 [2] Yilmaz C., Rangarajan AA., Schnetz K., 2020, The transcription regulator and c-di-GMP phosphodiesterase PdeL represses motility in Escherichia coli., J Bacteriol

 [3] Ogasawara H., Yamamoto K., Ishihama A., 2011, Role of the biofilm master regulator CsgD in cross-regulation between biofilm formation and flagellar synthesis., J Bacteriol 193(10):2587-97

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