RegulonDB

TRANSCRIPTION FACTOR:

Name:

CRP	Weight Matrix Tractordb tool

Connectivity class

Global Regulator

Sensing Class

Using internal synthesized signals

Synonym(s):

Cap, Csm, DNA-binding transcriptional dual regulator CRP, GurB

Gene name(s):

crp

Functional conformation(s):

CRP , CRP-cyclic-AMP

Coregulator(s):

AaeR, AcrR, AdiY, AgaR, AraC, ArcA, ArgP, ArgR, AscG, BasR, BolA, BtsR, CRP, CRP-Sxy, CaiF, ChbR, ComR, CpxR, Cra, CreB, CsgD, CspA, CsqR, CusR, CytR, DcuR, DeoR, DgoR, DksA-ppGpp, DnaA, DpiA, DsdC, EbgR, EnvY, EvgA, ExuR, FNR, FadR, FeaR, FhlA, Fis, FlhDC, FliZ, FrlR, FucR, Fur, GadE, GadE-RcsB, GadW, GadX, GalR, GalS, GatR, GcvA, GlaR, GlcC, GlpR, GlrR, GntR, GutM, H-NS, HU, HdfR, HipB, HprR, HyfR, HypT, IHF, IclR, IdnR, LacI, LeuO, LexA, LrhA, Lrp, LsrR, MalI, MalT, MarA, MarR, MatA, McbR, MelR, MetJ, MhpR, Mlc, MlrA, ModE, MprA, MqsA, MurR, Nac, NadR, NagC, NanR, NarL, NarP, NrdR, NsrR, NtrC, OmpR, OxyR, PaaX, PdhR, PhoB, PhoP, PlaR, PrpR, PurR, PuuR, QseB, RbsR, RcdA, RcsAB, RcsB, RcsB-BglJ, RhaR, RhaS, Rob, RspR, RstA, SdiA, SlyA, SoxR, SoxS, SrlR, StpA, TdcA, TdcR, TorR, TreR, UhpA, UidR, UlaR, UvrY, UxuR, XylR, YdeO, YjjQ, ZraR, ppGpp

Summary:

TF Summary ...[more]

TRANSCRIPTION FACTOR:

Info

Name:

MurR	Tractordb tool

Connectivity class

Local Regulator

Synonym(s):

DNA-binding transcriptional dual regulator MurR, YfeT

Gene name(s):

murR

Functional conformation(s):

MurR , MurR-N-acetyl-D-muramate 6-phosphate

Coregulator(s):

CRP, MurR

Summary:

TF Summary ...[more]

REGULATION EXERTED BY CRP,MurR

Info M3D | Colombos

KNOWN BINDING SITES (The central relative position is relative to the promoter +1)
CRP activator MurR repressor
Transcription Factor		Regulated		Binding Sites				Evidence	References
Functional conformation	Function	Promoter	Gene(s)	LeftPos	RigthPos	Central Rel-Pos	Sequence
MurR	repressor	murQp1	murQ , murP	2545714	2545729	-12.0	ctgtcaattcGGGATATATGATTCCAtacatctgca	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
CRP-cyclic-AMP	activator	murQp1	murQ , murP	2545651	2545672	-71.5	ccgcttaagtTCTTATGACGCTCTTCACACTCtgcgagtgta	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
CRP-cyclic-AMP	activator	murQp2	murQ , murP	2545651	2545672	-79.5	ccgcttaagtTCTTATGACGCTCTTCACACTCtgcgagtgta	[COMP-AINF-SIMILAR-TO-CONSENSUS] [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] [EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
MurR	repressor	murQp2	murQ , murP	2545714	2545729	-20.0	ctgtcaattcGGGATATATGATTCCAtacatctgca	[EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] [EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
MurR	repressor	murQp1	murQ , murP	2545682	2545697	-44.0	ctgcgagtgtAGACTCAATGATTCCTttaagcctgt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
MurR	repressor	murQp2	murQ , murP	2545682	2545697	-52.0	ctgcgagtgtAGACTCAATGATTCCTttaagcctgt	[COMP-AINF] [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] [EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
MurR	repressor	murQp	murQ , murP	2545682	2545697	-44.0	ctgcgagtgtAGACTCAATGATTCCTttaagcctgt	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
MurR	repressor	murQp	murQ , murP	2545714	2545729	-12.0	ctgtcaattcGGGATATATGATTCCAtacatctgca	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]
CRP-cyclic-AMP	activator	murQp	murQ , murP	2545651	2545672	-71.5	ccgcttaagtTCTTATGACGCTCTTCACACTCtgcgagtgta	[EXP-IEP-GENE-EXPRESSION-ANALYSIS]	[1]

Evidence:	[EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis [COMP-AINF-SIMILAR-TO-CONSENSUS] Automated inference based on similarity to consensus sequences [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] Binding of purified proteins [COMP-AINF] Inferred computationally without human oversight
Reference(s):	[1] Jaeger T., et al., 2008