RegulonDB evolutionary first Genes of Regulon

Summary of evolutionary conservation promoters regulated by TyrR

The evolutionary conservation of promoters is limited to Gammaproteobacteria and to sigma70 promoters. In general an promoter is conserved if, i) the position of the promoter from the gene start is conserved, or ii) the promoter sequence recognized by the sigma70 factor is conserved (p < 0.0001). To avoid redundancy, the orthologous regions were purged using the program Purge-Sequence from RSAtools. Orthologs consisted of BLAST reciprocal best hits using soft masking and Smith-Waterman alignments.

First gene Promoter name Evolutionary conservation ratio (nd) Footprint conservation
aroF aroFp 0.33
aroG aroGp 0.25
aroL aroLp 0.43
aroLp2 (nd)
aroP aroPp1 0.09
aroPp2 0.17
aroP aroPp1 0.09
aroPp2 0.17
folA folAp (nd)
mtr mtrp1 (nd)
mtrp2 0.04
tyrB tyrBp (nd)
tyrP tyrPp1 0.43
tyrPp2 (nd)
tyrR tyrRp 0.28
ycjXp (nd)