RegulonDB evolutionary first Genes of Regulon

Summary of evolutionary conservation promoters regulated by FadR

The evolutionary conservation of promoters is limited to Gammaproteobacteria and to sigma70 promoters. In general an promoter is conserved if, i) the position of the promoter from the gene start is conserved, or ii) the promoter sequence recognized by the sigma70 factor is conserved (p < 0.0001). To avoid redundancy, the orthologous regions were purged using the program Purge-Sequence from RSAtools. Orthologs consisted of BLAST reciprocal best hits using soft masking and Smith-Waterman alignments.

First gene Promoter name Evolutionary conservation ratio (nd) Footprint conservation
accA accAp1 0.13
accAp2 (nd)
accB accBp1 0.04
accBp2 (nd)
accD accDp 0.05
fabA fabAp 0.12
fabB fabBp (nd)
fabH fabHp (nd)
plsXp (nd)
rpmFp (nd)
fabI fabIp (nd)
fabIp1 (nd)
fadB fadBp 0.18
fadD fadDp 0.23
fadE fadEp (nd)
fadH fadHp (nd)
fadI fadIp 0.10
fadL fadLp (nd)
fadM fadMp1 (nd)
fadR fadRp1 0.13
fadRp2 (nd)
iclR iclRp (nd)
uspA uspAp1 0.24
uspAp2 (nd)
uspAp3 (nd)