RegulonDB evolutionary first Genes of Regulon

Summary of evolutionary conservation promoters regulated by LexA

The evolutionary conservation of promoters is limited to Gammaproteobacteria and to sigma70 promoters. In general an promoter is conserved if, i) the position of the promoter from the gene start is conserved, or ii) the promoter sequence recognized by the sigma70 factor is conserved (p < 0.0001). To avoid redundancy, the orthologous regions were purged using the program Purge-Sequence from RSAtools. Orthologs consisted of BLAST reciprocal best hits using soft masking and Smith-Waterman alignments.

First gene Promoter name Evolutionary conservation ratio (nd) Footprint conservation
cho chop 0.20
dinB dinBp 0.15
dinD dinDp (nd)
dinG dinGp 0.02
dinI dinIp (nd)
dinJ dinJp 0.10
dinQ dinQp (nd)
ftsK ftsKp1 0.10
ftsKp2 0.22
ftsL ftsLp1 (nd)
ftsLp2 (nd)
mraWp1 (nd)
mraZp 0.07
hokE hokEp (nd)
insK insKp (nd)
lexA lexAp 0.62
phr phrp (nd)
ybgAp1 (nd)
ybgAp2 (nd)
polB polBp 0.02
ptrA ptrAp (nd)
ptrAp (nd)
ptrA ptrAp (nd)
ptrAp (nd)
recA recAp 0.47
recAp 0.47
recA recAp 0.47
recAp 0.47
recN recNp 0.33
recQ recQp (nd)
rpsU rpsUp1 0.21
rpsUp1 0.21
rpsUp2 0.62
rpsUp3 (nd)
ruvA ruvAp1 (nd)
ruvAp2 (nd)
ruvA ruvAp1 (nd)
ruvAp2 (nd)
sbmC sbmCp1 (nd)
sbmCp2 (nd)
ssb ssbp1 0.11
ssbp2 0.03
ssbp3 0.03
sulA sulAp 0.18
symE symEp (nd)
tisB tisBp (nd)
umuD umuDp 0.15
uvrA uvrAp 0.13
uvrB uvrBp1 0.39
uvrBp2 0.25
uvrBp3 0.19
uvrB uvrBp1 0.39
uvrBp2 0.25
uvrBp3 0.19
uvrB uvrBp1 0.39
uvrBp2 0.25
uvrBp3 0.19
uvrC uvrCp3 0.26
uvrYp2 0.10
uvrD uvrDp1 0.41
uvrDp2 (nd)
uvrY uvrYp2 0.10
yafN dinBp 0.15
yafNp (nd)
ybfE ybfEp (nd)
ydjM ydjMp 0.15
yebG yebGp 0.06
yehF yehFp (nd)