RegulonDB Gene Evolutionary Conservation
Evolutionary conservation of the AsnC regulatory interaction in asnA orthologous genes

In general an interaction is conserved if there is a significant overrepresentation of TFBSs in the set of orthologous promoters of the target gene. The set of orthologous promoter for asnA was scanned with the annotated matrix for AsnC. In order to avoid bias due to an excessive representation of close genomes (i.e. several E. coli genomes) we masked the regulatory sequences that were too similar. Overrepresentation is calculated based on the binomial distribution, comparing the observed scores vs. the expected ones for the masked sequence set.


Ortholog predicted binding sitesasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_AsnC_sites.tab
Ortholog predicted binding sites graphasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_AsnC_sites.jpg
genesasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_query_genes.tab
Query sequenceasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_query_seq.fasta
OrthologsasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_bbh.tab
ortho sequencesasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_seq.fasta
Purged sequencesasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_seq_purged.fasta
Occ sigasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_AsnC_occ_sig.tab
Occ sig graphasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_AsnC_occ_sig.jpg
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Occ freq graphasnA_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_AsnC_occ_freq.jpg
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