RegulonDB Gene Evolutionary Conservation
Evolutionary conservation of the MntR regulatory interaction in dps orthologous genes

In general an interaction is conserved if there is a significant overrepresentation of TFBSs in the set of orthologous promoters of the target gene. The set of orthologous promoter for dps was scanned with the annotated matrix for MntR. In order to avoid bias due to an excessive representation of close genomes (i.e. several E. coli genomes) we masked the regulatory sequences that were too similar. Overrepresentation is calculated based on the binomial distribution, comparing the observed scores vs. the expected ones for the masked sequence set.


Ortholog predicted binding sitesdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_MntR_sites.tab
Ortholog predicted binding sites graphdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_MntR_sites.jpg
genesdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_query_genes.tab
Query sequencedps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_query_seq.fasta
Orthologsdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_bbh.tab
ortho sequencesdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_seq.fasta
Purged sequencesdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_ortho_seq_purged.fasta
Occ sigdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_MntR_occ_sig.tab
Occ sig graphdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_MntR_occ_sig.jpg
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Occ freq graphdps_Escherichia_coli_K_12_substr__MG1655_uid57779_Gammaproteobacteria_MntR_occ_freq.jpg
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