RegulonDB RegulonDB 11.1: Gene Form
   

betT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

betT betI yahV Cra PdeL ArcA ArcA BetI ArcA pdeLp2 pdeLp2 betTp betTp betIp betIp

Gene      
Name: betT    Texpresso search in the literature
Synonym(s): ECK0312, EG10112, b0314
Genome position(nucleotides): 329463 --> 331496
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.31
External database links:  
ASAP:
 ABE-0001080
CGSC:
 18505
ECHOBASE:
 EB0110
ECOLIHUB:
 betT
OU-MICROARRAY:
 b0314
STRING:
 511145.b0314
COLOMBOS: betT


Product      
Name: choline:H+ symporter
Synonym(s): BetT
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 75.842
Isoelectric point: 6.912
Motif(s):
 
Type Positions Sequence Comment
15 -> 35 PVVFYTSAGLILLFSLTTILF UniProt: Helical.
17 -> 501 VFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLK
54 -> 74 FGWYYLLAATLYIVFVVCIAC UniProt: Helical.
94 -> 114 LSWAAMLFAAGIGIDLMFFSV UniProt: Helical.
144 -> 164 FHYGLTGWSMYALMGMALGYF UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.18 - betaine biosynthesis
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
GO:0015220 - choline transmembrane transporter activity
biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0019285 - glycine betaine biosynthetic process from choline
GO:0055085 - transmembrane transport
GO:0071705 - nitrogen compound transport
GO:0015871 - choline transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0ABC9
ECOCYC:
 BETT-MONOMER
ECOLIWIKI:
 b0314
INTERPRO:
 IPR000060
INTERPRO:
 IPR018093
PANTHER:
 PTHR30047
PFAM:
 PF02028
PRIDE:
 P0ABC9
PRODB:
 PRO_000022210
PROSITE:
 PS01303
REFSEQ:
 NP_414848
UNIPROT:
 P0ABC9


Operon      
Name: betT         
Operon arrangement:
Transcription unit        Promoter
betT


Transcriptional Regulation      
Display Regulation             
Activated by: Cra
Repressed by: BetI, ArcA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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