RegulonDB RegulonDB 11.1: Gene Form
   

moeA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

moeA iaaA moeB fsaA gsiA NarL ArcA NarL FNR anti-anti-terminator anti-terminator terminator iaaAp iaaAp moeAp moeAp

Gene      
Name: moeA    Texpresso search in the literature
Synonym(s): ECK0817, EG10153, b0827, bisB, chlE, narE
Genome position(nucleotides): 865129 <-- 866364
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 56.39
External database links:  
ASAP:
 ABE-0002823
CGSC:
 919
ECHOBASE:
 EB0151
ECOLIHUB:
 moeA
MIM:
 615501
OU-MICROARRAY:
 b0827
STRING:
 511145.b0827
COLOMBOS: moeA


Product      
Name: molybdopterin molybdotransferase
Synonym(s): BisB, ChlE, MoeA, NarE
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 44.067
Isoelectric point: 4.774
Motif(s):
 
Type Positions Sequence Comment
9 -> 168 SLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLG
182 -> 317 LFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLA
332 -> 404 RVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPF

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.4 - molybdenum
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0005515 - protein binding
GO:0016740 - transferase activity
GO:0046872 - metal ion binding
GO:0042802 - identical protein binding
GO:0042803 - protein homodimerization activity
GO:0061599 - molybdopterin molybdotransferase activity
biological_process GO:0006777 - Mo-molybdopterin cofactor biosynthetic process
GO:0032324 - molybdopterin cofactor biosynthetic process
GO:0018315 - molybdenum incorporation into molybdenum-molybdopterin complex
External database links:  
ALPHAFOLD:
 P12281
DIP:
 DIP-10240N
ECOCYC:
 EG10153-MONOMER
ECOLIWIKI:
 b0827
INTERPRO:
 IPR038987
INTERPRO:
 IPR005110
INTERPRO:
 IPR001453
INTERPRO:
 IPR005111
INTERPRO:
 IPR036688
INTERPRO:
 IPR008284
INTERPRO:
 IPR036135
INTERPRO:
 IPR036425
MODBASE:
 P12281
PANTHER:
 PTHR10192
PDB:
 2NRS
PDB:
 2NRP
PDB:
 2NRO
PDB:
 2NQV
PDB:
 2NQU
PDB:
 2NQS
PDB:
 2NQR
PDB:
 2NQQ
PDB:
 2NQN
PDB:
 2NQM
PDB:
 2NQK
PDB:
 1G8R
PDB:
 1FC5
PDB:
 1G8L
PFAM:
 PF00994
PFAM:
 PF03453
PFAM:
 PF03454
PRIDE:
 P12281
PROSITE:
 PS01079
REFSEQ:
 NP_415348
SMART:
 SM00852
SMR:
 P12281
UNIPROT:
 P12281


Operon      
Name: moeAB         
Operon arrangement:
Transcription unit        Promoter
moeAB


Transcriptional Regulation      
Display Regulation             
Activated by: NsrR, ArcA, NarL
Repressed by: FNR


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB