Gene
Name:	dcm
Synonym(s):	ECK1959, EG10211, b1961, mec
Genome position(nucleotides):	2030899 <-- 2032317
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.15
External database links:

ASAP:	ABE-0006509
CGSC:	874
ECHOBASE:	EB0207
ECOLIHUB:	dcm
MIM:	604121
MIM:	614116
OU-MICROARRAY:	b1961
STRING:	511145.b1961
COLOMBOS:	dcm

Reference(s)
[1] Backman K., 1980, A cautionary note on the use of certain restriction endonucleases with methylated substrates., Gene 11(1-2):169-71
[2] Barbe J., Gibert I., Guerrero R., 1986, 5-Azacytidine: survival and induction of the SOS response in Escherichia coli K-12., Mutat Res 166(1):9-16
[3] Bhagwat AS., Roberts RJ., 1987, Genetic analysis of the 5-azacytidine sensitivity of Escherichia coli K-12., J Bacteriol 169(4):1537-46
[4] Bhagwat AS., Sohail A., Roberts RJ., 1986, Cloning and characterization of the dcm locus of Escherichia coli K-12., J Bacteriol 166(3):751-5
[5] Dreiseikelmann B., Wackernagel W., 1981, Absence in Bacillus subtilis and Staphylococcus aureus of the sequence-specific deoxyribonucleic acid methylation that is conferred in Escherichia coli K-12 by the dam and dcm enzymes., J Bacteriol 147(1):259-61
[6] Gomez-Eichelmann MC., Alvarez G., 1985, Genetic expression and gyrase dependence of methylated and undermethylated DNA in Escherichia coli., Biochim Biophys Acta 825(3):335-8
[7] Hanck T., Gerwin N., Fritz HJ., 1989, Nucleotide sequence of the dcm locus of Escherichia coli K12., Nucleic Acids Res 17(14):5844
[8] Hattman S., Schlagman S., Cousens L., 1973, Isolation of a mutant of Escherichia coli defective in cytosine-specific deoxyribonucleic acid methylase activity and in partial protection of bacteriophage lambda against restriction by cells containing the N-3 drug-resistance factor., J Bacteriol 115(3):1103-7
[9] Hughes JA., Brown LR., Ferro AJ., 1987, Expression of the cloned coliphage T3 S-adenosylmethionine hydrolase gene inhibits DNA methylation and polyamine biosynthesis in Escherichia coli., J Bacteriol 169(8):3625-32
[10] Korba BE., Hays JB., 1982, Partially deficient methylation of cytosine in DNA at CCATGG sites stimulates genetic recombination of bacteriophage lambda., Cell 28(3):531-41
[11] Kruger DH., Schroeder C., Reuter M., Bogdarina IG., Buryanov YI., Bickle TA., 1985, DNA methylation of bacterial viruses T3 and T7 by different DNA methylases in Escherichia coli K12 cells., Eur J Biochem 150(2):323-30
[12] Lal D., Som S., Friedman S., 1988, Survival and mutagenic effects of 5-azacytidine in Escherichia coli., Mutat Res 193(3):229-36
[13] Lee SY., Butler D., Kleckner N., 1987, Efficient Tn10 transposition into a DNA insertion hot spot in vivo requires the 5-methyl groups of symmetrically disposed thymines within the hot-spot consensus sequence., Proc Natl Acad Sci U S A 84(22):7876-80
[14] Lieb M., Allen E., Read D., 1986, Very short patch mismatch repair in phage lambda: repair sites and length of repair tracts., Genetics 114(4):1041-60
[15] Lundblad V., Kleckner N., 1985, Mismatch repair mutations of Escherichia coli K12 enhance transposon excision., Genetics 109(1):3-19
[16] May MS., Hattaman S., 1975, Deoxyribonucleic acid-cytosine methylation by host- and plasmid-controlled enzymes., J Bacteriol 122(1):129-38
[17] Pinney, R. J.., Tribe, M. J.., 1977, Resistance to acridines and thymineless death in a mec- mutant of Escherichia coli, J Pharm Pharmacol 29 Suppl:12P
[18] Shenoy S., Ehrlich KC., Ehrlich M., 1987, Repair of thymine.guanine and uracil.guanine mismatched base-pairs in bacteriophage M13mp18 DNA heteroduplexes., J Mol Biol 197(4):617-26
[19] Szyf M., Avraham-Haetzni K., Reifman A., Shlomai J., Kaplan F., Oppenheim A., Razin A., 1984, DNA methylation pattern is determined by the intracellular level of the methylase., Proc Natl Acad Sci U S A 81(11):3278-82
[20] Szyf M., Gruenbaum Y., Urieli-Shoval S., Razin A., 1982, Studies on the biological role of DNA methylation: V. The pattern of E.coli DNA methylation., Nucleic Acids Res 10(22):7247-59
[21] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

RNA cis-regulatory element

Attenuation:	Translational