RegulonDB RegulonDB 11.1: Gene Form
   

fimF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fimD fimF fimG TSS_5141 TSS_5141 TSS_5140 TSS_5140

Gene      
Name: fimF    Texpresso search in the literature
Synonym(s): ECK4309, EG10313, b4318
Genome position(nucleotides): 4547742 --> 4548272
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 49.53
External database links:  
ASAP:
 ABE-0014153
CGSC:
 18343
ECHOBASE:
 EB0309
ECOLIHUB:
 fimF
OU-MICROARRAY:
 b4318
STRING:
 511145.b4318
COLOMBOS: fimF


Product      
Name: type 1 fimbriae minor subunit FimF
Synonym(s): FimF
Sequence: Get amino acid sequence Fasta Format
Cellular location: pilus,extracellular space
Molecular weight: 18.715
Isoelectric point: 7.439
Motif(s):
 
Type Positions Sequence Comment
1 -> 20 MRNKPFYLLCAFLWLAVSHA
21 -> 176 LAADSTITIRGYVRDNGCSVAAESTNFTVDLMENAAKQFNNIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLALENTVSAASGLGIQLLNEQQNQIPLNAPSSALSWTTLTPGKPNTLNFYARLMATQVPVTAGHINATATFTLEYQ UniProt: Protein FimF.
28 -> 176 TIRGYVRDNGCSVAAESTNFTVDLMENAAKQFNNIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLALENTVSAASGLGIQLLNEQQNQIPLNAPSSALSWTTLTPGKPNTLNFYARLMATQVPVTAGHINATATFTLEYQ
70 -> 70 P UniProt: In Ref. 1; CAA29154..
76 -> 76 S UniProt: In Ref. 1; CAA29154..

 
Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.5 - pilus
Gene Ontology Terms (GO)  
cellular_component GO:0009419 - pilus tip
GO:0009289 - pilus
GO:0005576 - extracellular region
biological_process GO:0007638 - mechanosensory behavior
GO:0007155 - cell adhesion
GO:0009297 - pilus assembly
GO:0043709 - cell adhesion involved in single-species biofilm formation
GO:0031589 - cell-substrate adhesion
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P08189
DIP:
 DIP-9614N
ECOCYC:
 EG10313-MONOMER
ECOLIWIKI:
 b4318
INTERPRO:
 IPR036937
INTERPRO:
 IPR008966
INTERPRO:
 IPR000259
MINT:
 P08189
MODBASE:
 P08189
PDB:
 5IQN
PDB:
 5IQM
PDB:
 6E14
PDB:
 6E15
PDB:
 4XOB
PDB:
 5IQO
PDB:
 2JMR
PDB:
 3BFQ
PDB:
 3BFW
PDB:
 3BWU
PDB:
 3JWN
PDB:
 4J3O
PFAM:
 PF00419
PRIDE:
 P08189
PRODB:
 PRO_000022621
REFSEQ:
 NP_418738
SMR:
 P08189
UNIPROT:
 P08189


Operon      
Name: fimAICDFGH         
Operon arrangement:
Transcription unit        Promoter
fimAICDFGH


Transcriptional Regulation      
Display Regulation             
Activated by: H-NS, IHF, Lrp, QseB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_5140 4545183 forward nd [RS-EPT-CBR] [1]
  promoter TSS_5141 4547980 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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